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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
6.97
Human Site:
S1080
Identified Species:
15.33
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
S1080
G
S
Q
T
D
G
R
S
Q
P
R
T
L
G
H
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
S1077
P
C
P
S
K
S
L
S
P
K
Q
H
L
A
P
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
S1087
S
S
Q
S
D
G
R
S
Q
P
R
T
P
G
H
Dog
Lupus familis
XP_546733
1387
151432
G1067
Y
H
G
G
G
P
G
G
V
C
E
G
T
P
S
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
G1161
H
N
G
G
I
S
S
G
P
R
E
G
T
S
G
Rat
Rattus norvegicus
Q62688
1096
122754
L789
T
F
E
F
Q
V
N
L
P
E
L
T
M
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
I330
G
E
V
S
E
E
E
I
T
S
S
D
E
E
T
Frog
Xenopus laevis
Q32NH8
758
87399
S451
L
E
E
Q
P
D
D
S
L
G
E
V
S
D
E
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S477
W
T
S
F
T
N
S
S
D
E
E
S
V
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
R1011
H
K
S
V
K
E
K
R
L
E
M
E
K
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
I1388
K
P
E
Q
E
I
E
I
Q
E
R
E
I
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
13.3
80
0
N.A.
0
6.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
26.6
86.6
0
N.A.
6.6
20
N.A.
N.A.
20
13.3
26.6
N.A.
6.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
19
10
10
0
10
0
0
10
0
10
0
% D
% Glu:
0
19
28
0
19
19
19
0
0
37
37
19
10
10
10
% E
% Phe:
0
10
0
19
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
19
19
10
19
10
19
0
10
0
19
0
28
19
% G
% His:
19
10
0
0
0
0
0
0
0
0
0
10
0
0
19
% H
% Ile:
0
0
0
0
10
10
0
19
0
0
0
0
10
0
0
% I
% Lys:
10
10
0
0
19
0
10
0
0
10
0
0
10
10
0
% K
% Leu:
10
0
0
0
0
0
10
10
19
0
10
0
19
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% M
% Asn:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
10
0
10
10
0
0
28
19
0
0
10
10
10
% P
% Gln:
0
0
19
19
10
0
0
0
28
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
19
10
0
10
28
0
0
0
10
% R
% Ser:
10
19
19
28
0
19
19
46
0
10
10
10
10
10
10
% S
% Thr:
10
10
0
10
10
0
0
0
10
0
0
28
19
0
10
% T
% Val:
0
0
10
10
0
10
0
0
10
0
0
10
10
10
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _