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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
22.73
Human Site:
S491
Identified Species:
50
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
S491
G
E
V
S
D
E
D
S
A
D
E
I
D
D
D
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
S476
G
E
V
S
D
E
D
S
A
D
E
I
E
D
E
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
S494
G
E
V
S
D
E
D
S
A
D
E
I
D
D
D
Dog
Lupus familis
XP_546733
1387
151432
S472
G
E
V
S
D
E
D
S
A
D
E
I
D
E
D
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
S565
G
E
V
S
D
E
D
S
A
D
E
M
E
D
D
Rat
Rattus norvegicus
Q62688
1096
122754
D255
V
F
E
A
A
D
V
D
G
N
G
I
M
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
N465
R
R
K
I
I
I
K
N
K
K
K
H
H
H
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
S564
G
E
V
S
E
E
D
S
A
D
E
L
D
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
86.6
100
93.3
N.A.
86.6
6.6
N.A.
N.A.
0
0
0
N.A.
0
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
N.A.
0
0
0
N.A.
13.3
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
0
55
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
46
10
55
10
0
55
0
0
37
37
46
% D
% Glu:
0
55
10
0
10
55
0
0
0
0
55
0
19
19
19
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
55
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
10
10
10
% H
% Ile:
0
0
0
10
10
10
0
0
0
0
0
46
0
0
0
% I
% Lys:
0
0
10
0
0
0
10
0
10
10
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
55
0
0
0
55
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
55
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _