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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRGAP2 All Species: 26.97
Human Site: S135 Identified Species: 98.89
UniProt: O75044 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75044 NP_001036223.1 1071 120881 S135 F V Q V S E D S G R L F K K S
Chimpanzee Pan troglodytes XP_514148 1084 122320 S135 F V Q V S E D S G R L F K K S
Rhesus Macaque Macaca mulatta XP_001089021 1071 120861 S135 F V Q V S E D S G R L F K K S
Dog Lupus familis XP_848803 1071 120801 S135 F V Q V S E D S G R L F K K S
Cat Felis silvestris
Mouse Mus musculus Q91Z67 1071 120780 S135 F V Q V S E D S G R L F K K S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417972 1073 121031 S135 F V Q V S E D S G R L F K K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001041700 1100 123548 S135 F A Q I S E D S G R L F K K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 99.3 98.7 N.A. 98.1 N.A. N.A. N.A. 93.8 N.A. 75 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.7 99.6 99.5 N.A. 99 N.A. N.A. N.A. 96.2 N.A. 84.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. 100 N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % E
% Phe: 100 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 100 100 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % R
% Ser: 0 0 0 0 100 0 0 100 0 0 0 0 0 0 100 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 86 0 86 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _