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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOS1AP
All Species:
23.64
Human Site:
S460
Identified Species:
52
UniProt:
O75052
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75052
NP_055512.1
506
56150
S460
E
L
I
K
F
R
E
S
G
I
A
S
E
Y
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851837
1241
132437
A649
E
I
N
R
T
A
G
A
Q
L
A
G
G
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3A8
503
55833
S457
E
L
I
K
F
R
E
S
G
I
A
S
E
Y
E
Rat
Rattus norvegicus
O54960
503
55846
S457
E
L
I
K
F
R
E
S
G
I
A
S
E
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517303
468
51412
S422
E
P
I
R
F
R
E
S
G
I
A
S
E
Y
E
Chicken
Gallus gallus
XP_422215
496
55060
S450
E
L
L
K
F
R
E
S
G
I
A
S
E
Y
E
Frog
Xenopus laevis
NP_001087466
674
75343
S616
D
L
I
H
K
E
K
S
E
I
S
L
K
V
I
Zebra Danio
Brachydanio rerio
XP_001331962
675
74621
S540
V
V
A
S
P
E
S
S
F
V
S
S
P
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8SXX4
698
77261
R660
T
D
E
A
G
H
Q
R
K
L
S
A
T
P
S
Honey Bee
Apis mellifera
XP_396475
604
67840
T566
N
V
Q
K
N
L
A
T
I
L
R
T
T
G
P
Nematode Worm
Caenorhab. elegans
Q8STF6
887
99549
V791
K
I
Q
P
K
V
D
V
F
R
K
K
T
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
31.3
N.A.
94.2
94
N.A.
76
80.4
52.3
53.3
N.A.
29.9
32.4
31.7
N.A.
Protein Similarity:
100
N.A.
N.A.
34.4
N.A.
95.4
95.4
N.A.
81
86.9
61.4
61.9
N.A.
44.7
48
43.6
N.A.
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
100
100
N.A.
86.6
93.3
26.6
13.3
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
40
N.A.
100
100
N.A.
93.3
100
53.3
40
N.A.
26.6
33.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
10
10
10
0
0
55
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
10
0
0
0
0
0
0
10
0
% D
% Glu:
55
0
10
0
0
19
46
0
10
0
0
0
46
0
46
% E
% Phe:
0
0
0
0
46
0
0
0
19
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
46
0
0
10
10
10
0
% G
% His:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
46
0
0
0
0
0
10
55
0
0
0
0
10
% I
% Lys:
10
0
0
46
19
0
10
0
10
0
10
10
10
0
19
% K
% Leu:
0
46
10
0
0
10
0
0
0
28
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
10
10
0
0
0
0
0
0
0
10
10
10
% P
% Gln:
0
0
19
0
0
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
19
0
46
0
10
0
10
10
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
10
64
0
0
28
55
0
0
10
% S
% Thr:
10
0
0
0
10
0
0
10
0
0
0
10
28
0
0
% T
% Val:
10
19
0
0
0
10
0
10
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _