KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGSF3
All Species:
25.76
Human Site:
S199
Identified Species:
62.96
UniProt:
O75054
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75054
NP_001007238.1
1194
135196
S199
P
V
E
V
I
S
L
S
R
D
F
M
L
H
S
Chimpanzee
Pan troglodytes
XP_001147567
1192
134961
S199
P
V
E
V
I
S
L
S
R
D
F
M
L
H
S
Rhesus Macaque
Macaca mulatta
XP_001102991
1494
166412
S478
P
V
E
V
I
S
L
S
R
D
F
M
L
H
S
Dog
Lupus familis
XP_540257
1232
139134
S243
P
V
E
V
I
S
L
S
R
D
F
V
L
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQA6
1194
134692
S199
P
V
E
V
I
S
L
S
R
D
F
I
L
H
S
Rat
Rattus norvegicus
Q62786
879
98712
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507744
770
83805
Chicken
Gallus gallus
XP_416662
1201
136191
S223
P
V
E
I
I
S
L
S
R
D
F
V
L
R
A
Frog
Xenopus laevis
Q5U5A3
1165
129541
T199
E
H
E
I
I
S
L
T
Q
N
L
S
V
R
A
Zebra Danio
Brachydanio rerio
NP_001153138
1042
116932
Y79
V
S
T
S
Q
H
N
Y
A
Y
A
L
Y
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
78.7
90.5
N.A.
92.7
24
N.A.
28.3
74.1
56.1
47.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
79.4
94.2
N.A.
97.3
38.3
N.A.
38.8
83.8
71
64.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
0
73.3
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
0
93.3
66.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% D
% Glu:
10
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
10
0
0
0
0
0
0
0
50
0
% H
% Ile:
0
0
0
20
70
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
70
0
0
0
10
10
60
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
30
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
60
0
0
0
0
20
0
% R
% Ser:
0
10
0
10
0
70
0
60
0
0
0
10
0
0
50
% S
% Thr:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
10
60
0
50
0
0
0
0
0
0
0
20
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _