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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IGSF3 All Species: 24.24
Human Site: T282 Identified Species: 59.26
UniProt: O75054 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75054 NP_001007238.1 1194 135196 T282 Q P T D K E F T V R L E T E K
Chimpanzee Pan troglodytes XP_001147567 1192 134961 T282 Q P T D K E F T V R L E T E K
Rhesus Macaque Macaca mulatta XP_001102991 1494 166412 T561 Q P T D K E F T V R L E T E K
Dog Lupus familis XP_540257 1232 139134 T326 Q P T D K E F T V R L E T E K
Cat Felis silvestris
Mouse Mus musculus Q6ZQA6 1194 134692 T282 Q P T D K E F T V R L E T D K
Rat Rattus norvegicus Q62786 879 98712
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507744 770 83805
Chicken Gallus gallus XP_416662 1201 136191 S306 Q A T D K E F S V R L E T E K
Frog Xenopus laevis Q5U5A3 1165 129541 N282 Q P T D K E F N V R L E T E R
Zebra Danio Brachydanio rerio NP_001153138 1042 116932 T162 L A K V E G D T L Q L S C E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 78.7 90.5 N.A. 92.7 24 N.A. 28.3 74.1 56.1 47.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 79.4 94.2 N.A. 97.3 38.3 N.A. 38.8 83.8 71 64.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 0 N.A. 0 86.6 86.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 0 N.A. 0 93.3 93.3 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 70 0 0 10 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 10 70 0 0 0 0 0 70 0 70 0 % E
% Phe: 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 70 0 0 0 0 0 0 0 0 0 60 % K
% Leu: 10 0 0 0 0 0 0 0 10 0 80 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 70 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 10 % R
% Ser: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % S
% Thr: 0 0 70 0 0 0 0 60 0 0 0 0 70 0 0 % T
% Val: 0 0 0 10 0 0 0 0 70 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _