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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0494 All Species: 9.7
Human Site: T258 Identified Species: 30.48
UniProt: O75071 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75071 NP_055589.1 495 55031 T258 T S E L D N K T H S E N L K Q
Chimpanzee Pan troglodytes XP_524573 699 75450 T462 T S E L D N K T H S E N L K Q
Rhesus Macaque Macaca mulatta XP_001096587 383 42258 W151 E M G L N K V W I N I T E K N
Dog Lupus familis XP_539624 565 62275 T328 I S E F D N K T H S E N L K Q
Cat Felis silvestris
Mouse Mus musculus Q8BGQ6 484 53675 N249 S P P S E L D N K S H S E S A
Rat Rattus norvegicus NP_001100147 484 53459 N249 P P P S E L D N R T H S E S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001087373 461 50310 E228 T S V H N D V E T M Q A A T E
Zebra Danio Brachydanio rerio NP_996958 255 27034 S23 L I G G R R K S Q S C G H R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.3 69.9 76.4 N.A. 79.3 82.4 N.A. N.A. N.A. 48.6 30.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.5 73.3 82.3 N.A. 89.6 90.5 N.A. N.A. N.A. 64.6 38.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 86.6 N.A. 6.6 0 N.A. N.A. N.A. 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 86.6 N.A. 26.6 20 N.A. N.A. N.A. 40 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 13 13 0 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % C
% Asp: 0 0 0 0 38 13 25 0 0 0 0 0 0 0 0 % D
% Glu: 13 0 38 0 25 0 0 13 0 0 38 0 38 0 13 % E
% Phe: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 25 13 0 0 0 0 0 0 0 13 0 0 0 % G
% His: 0 0 0 13 0 0 0 0 38 0 25 0 13 0 0 % H
% Ile: 13 13 0 0 0 0 0 0 13 0 13 0 0 0 0 % I
% Lys: 0 0 0 0 0 13 50 0 13 0 0 0 0 50 0 % K
% Leu: 13 0 0 38 0 25 0 0 0 0 0 0 38 0 13 % L
% Met: 0 13 0 0 0 0 0 0 0 13 0 0 0 0 0 % M
% Asn: 0 0 0 0 25 38 0 25 0 13 0 38 0 0 13 % N
% Pro: 13 25 25 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 13 0 13 0 0 0 38 % Q
% Arg: 0 0 0 0 13 13 0 0 13 0 0 0 0 13 0 % R
% Ser: 13 50 0 25 0 0 0 13 0 63 0 25 0 25 0 % S
% Thr: 38 0 0 0 0 0 0 38 13 13 0 13 0 13 0 % T
% Val: 0 0 13 0 0 0 25 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _