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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP3
All Species:
21.82
Human Site:
S524
Identified Species:
68.57
UniProt:
O75074
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75074
NP_002324.2
770
82884
S524
G
C
A
F
K
L
Y
S
L
R
T
Q
E
Y
R
Chimpanzee
Pan troglodytes
XP_001153279
770
82855
S524
G
C
A
F
K
L
Y
S
L
R
T
Q
E
Y
R
Rhesus Macaque
Macaca mulatta
XP_001088056
770
82672
S524
G
C
A
F
K
L
Y
S
L
R
T
Q
E
Y
R
Dog
Lupus familis
XP_541714
704
74481
S493
P
D
D
P
G
P
G
S
D
G
A
R
A
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUJ9
858
94533
S520
G
C
T
C
K
L
Y
S
L
R
M
F
E
R
R
Rat
Rattus norvegicus
O88204
770
82998
S524
G
C
A
F
K
L
Y
S
L
R
T
Q
E
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512109
809
89197
N550
P
I
A
G
R
S
S
N
I
W
N
R
I
F
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124106
820
90490
S496
G
C
A
F
K
L
Y
S
L
R
T
R
E
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.3
77.5
N.A.
42.8
93.1
N.A.
43.5
N.A.
N.A.
55.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
98.4
79.6
N.A.
56.7
94
N.A.
57.3
N.A.
N.A.
68.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
66.6
100
N.A.
6.6
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
66.6
100
N.A.
40
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
75
0
0
0
0
0
0
0
13
0
13
0
0
% A
% Cys:
0
75
0
13
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
13
0
0
0
0
0
13
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% E
% Phe:
0
0
0
63
0
0
0
0
0
0
0
13
0
13
0
% F
% Gly:
75
0
0
13
13
0
13
0
0
13
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
0
0
0
13
0
0
0
13
0
0
% I
% Lys:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
75
0
0
75
0
0
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
13
0
0
0
13
% N
% Pro:
25
0
0
13
0
13
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% Q
% Arg:
0
0
0
0
13
0
0
0
0
75
0
38
0
13
75
% R
% Ser:
0
0
0
0
0
13
13
88
0
0
0
0
0
0
0
% S
% Thr:
0
0
13
0
0
0
0
0
0
0
63
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
75
0
0
0
0
0
0
63
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _