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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM11
All Species:
17.27
Human Site:
Y496
Identified Species:
47.5
UniProt:
O75078
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75078
NP_002381.2
769
83418
Y496
L
C
C
R
R
C
K
Y
E
P
R
G
V
S
C
Chimpanzee
Pan troglodytes
XP_511556
860
92903
Y587
L
C
C
R
R
C
K
Y
E
P
R
G
V
S
C
Rhesus Macaque
Macaca mulatta
XP_001104527
899
100254
F496
L
C
C
K
K
C
K
F
Q
P
M
G
T
V
C
Dog
Lupus familis
XP_848544
965
103580
Y702
L
C
C
R
R
C
K
Y
E
P
R
G
V
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1V4
773
84116
Y500
L
C
C
R
R
C
K
Y
E
P
R
G
V
S
C
Rat
Rattus norvegicus
Q9QYV0
816
88034
L475
P
C
C
Q
N
C
K
L
Q
P
A
G
W
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001138702
758
84411
F494
C
C
N
T
S
C
L
F
F
P
R
G
Y
D
C
Frog
Xenopus laevis
O42596
935
104143
F498
L
C
C
S
N
C
K
F
N
P
K
E
M
L
C
Zebra Danio
Brachydanio rerio
XP_695529
774
85179
Y499
L
C
C
N
R
C
K
Y
E
Q
R
G
V
I
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.2
45.9
75.3
N.A.
94.3
29.7
N.A.
N.A.
50.3
44.2
62
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.7
58.9
76.3
N.A.
95.5
43.7
N.A.
N.A.
62.9
56.6
73.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
100
N.A.
100
46.6
N.A.
N.A.
40
46.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
100
N.A.
100
60
N.A.
N.A.
46.6
66.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
12
100
89
0
0
100
0
0
0
0
0
0
0
0
100
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
56
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
34
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
89
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
0
0
0
12
12
0
89
0
0
0
12
0
0
0
0
% K
% Leu:
78
0
0
0
0
0
12
12
0
0
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% M
% Asn:
0
0
12
12
23
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
0
89
0
0
0
0
0
% P
% Gln:
0
0
0
12
0
0
0
0
23
12
0
0
0
12
0
% Q
% Arg:
0
0
0
45
56
0
0
0
0
0
67
0
0
0
0
% R
% Ser:
0
0
0
12
12
0
0
0
0
0
0
0
0
45
0
% S
% Thr:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
56
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _