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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR1 All Species: 30.61
Human Site: S335 Identified Species: 51.79
UniProt: O75083 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75083 NP_005103.2 606 66194 S335 V H K N G G K S Y I Y S G S H
Chimpanzee Pan troglodytes XP_001158647 606 66166 S335 V H K N G G K S Y I Y S G S H
Rhesus Macaque Macaca mulatta XP_001097937 606 66149 S335 V H K N G G K S Y I Y S G S H
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88342 606 66388 S335 V H R N G G K S Y I Y S G S H
Rat Rattus norvegicus Q5RKI0 606 66163 S335 V H K N G G K S Y I Y S G S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508159 447 48280 Y188 S H D G H I N Y W D S E T G E
Chicken Gallus gallus O93277 609 66548 S337 V H K N G G K S Y I Y S G S N
Frog Xenopus laevis Q6PAX7 607 66151 S335 V D K S D G R S T I Y T G S H
Zebra Danio Brachydanio rerio NP_957333 606 66494 T335 V H K A D G R T S I Y S G S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VU68 608 66531 I340 L S D D R S T I Y T G S H D G
Honey Bee Apis mellifera XP_624088 602 66930 I334 L S P D R S T I Y T G S H D G
Nematode Worm Caenorhab. elegans Q11176 611 65305 K337 L S S S A D G K T L F S A D A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FLX9 473 52879 F214 L S S P C R R F V T S S K D G
Baker's Yeast Sacchar. cerevisiae P46680 615 67307 I351 A L T V N P L I S G S Y D G R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.1 N.A. N.A. 95.2 95.8 N.A. 67.1 88.1 80.4 74.9 N.A. 48.1 48.5 40 N.A.
Protein Similarity: 100 99.6 99.5 N.A. N.A. 98.6 99 N.A. 70.9 94.5 90.1 87.6 N.A. 68.5 68.6 59 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 93.3 100 N.A. 6.6 93.3 60 66.6 N.A. 13.3 13.3 6.6 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 13.3 100 80 80 N.A. 26.6 26.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.9 29.7 N.A.
Protein Similarity: N.A. N.A. N.A. 36.9 48.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 8 0 0 0 0 0 0 0 8 0 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 15 15 15 8 0 0 0 8 0 0 8 29 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 8 43 58 8 0 0 8 15 0 58 15 22 % G
% His: 0 58 0 0 8 0 0 0 0 0 0 0 15 0 50 % H
% Ile: 0 0 0 0 0 8 0 22 0 58 0 0 0 0 0 % I
% Lys: 0 0 50 0 0 0 43 8 0 0 0 0 8 0 0 % K
% Leu: 29 8 0 0 0 0 8 0 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 43 8 0 8 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 8 8 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 15 8 22 0 0 0 0 0 0 0 8 % R
% Ser: 8 29 15 15 0 15 0 50 15 0 22 79 0 58 0 % S
% Thr: 0 0 8 0 0 0 15 8 15 22 0 8 8 0 0 % T
% Val: 58 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 58 0 58 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _