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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR1
All Species:
32.73
Human Site:
S383
Identified Species:
55.38
UniProt:
O75083
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75083
NP_005103.2
606
66194
S383
S
G
Q
L
I
S
C
S
M
D
D
T
V
R
Y
Chimpanzee
Pan troglodytes
XP_001158647
606
66166
S383
S
G
Q
L
I
S
C
S
M
D
D
T
V
R
Y
Rhesus Macaque
Macaca mulatta
XP_001097937
606
66149
S383
S
G
Q
L
I
S
C
S
M
D
D
T
V
R
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88342
606
66388
S383
S
E
Q
L
V
S
C
S
M
D
D
T
V
R
Y
Rat
Rattus norvegicus
Q5RKI0
606
66163
S383
S
G
Q
L
V
S
C
S
M
D
D
T
V
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508159
447
48280
K236
R
Y
T
S
L
L
H
K
D
Y
S
G
Q
G
V
Chicken
Gallus gallus
O93277
609
66548
S385
M
D
Q
L
V
T
C
S
M
D
D
T
V
R
Y
Frog
Xenopus laevis
Q6PAX7
607
66151
S383
S
S
Q
L
I
T
C
S
M
D
D
T
L
R
Y
Zebra Danio
Brachydanio rerio
NP_957333
606
66494
S383
A
E
R
L
V
T
C
S
M
D
D
T
V
R
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU68
608
66531
D388
V
Y
T
C
G
I
D
D
S
L
R
Q
F
S
V
Honey Bee
Apis mellifera
XP_624088
602
66930
D382
L
Y
T
A
G
I
D
D
T
L
R
L
V
D
I
Nematode Worm
Caenorhab. elegans
Q11176
611
65305
S385
K
G
D
L
F
T
V
S
W
D
D
H
L
K
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
C262
I
Y
T
G
S
Q
D
C
T
I
K
M
W
E
T
Baker's Yeast
Sacchar. cerevisiae
P46680
615
67307
G399
D
D
T
L
K
V
N
G
I
T
K
H
E
F
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
N.A.
N.A.
95.2
95.8
N.A.
67.1
88.1
80.4
74.9
N.A.
48.1
48.5
40
N.A.
Protein Similarity:
100
99.6
99.5
N.A.
N.A.
98.6
99
N.A.
70.9
94.5
90.1
87.6
N.A.
68.5
68.6
59
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
93.3
N.A.
0
73.3
80
66.6
N.A.
0
6.6
33.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
100
N.A.
6.6
86.6
93.3
93.3
N.A.
0
6.6
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.9
48.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
58
8
0
0
0
0
0
0
0
% C
% Asp:
8
15
8
0
0
0
22
15
8
65
65
0
0
8
0
% D
% Glu:
0
15
0
0
0
0
0
0
0
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
36
0
8
15
0
0
8
0
0
0
8
0
8
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
15
0
0
0
% H
% Ile:
8
0
0
0
29
15
0
0
8
8
0
0
0
0
8
% I
% Lys:
8
0
0
0
8
0
0
8
0
0
15
0
0
8
0
% K
% Leu:
8
0
0
72
8
8
0
0
0
15
0
8
15
0
0
% L
% Met:
8
0
0
0
0
0
0
0
58
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
50
0
0
8
0
0
0
0
0
8
8
0
0
% Q
% Arg:
8
0
8
0
0
0
0
0
0
0
15
0
0
58
0
% R
% Ser:
43
8
0
8
8
36
0
65
8
0
8
0
0
8
0
% S
% Thr:
0
0
36
0
0
29
0
0
15
8
0
58
0
0
8
% T
% Val:
8
0
0
0
29
8
8
0
0
0
0
0
58
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% W
% Tyr:
0
29
0
0
0
0
0
0
0
8
0
0
0
0
58
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _