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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR1
All Species:
30.3
Human Site:
S594
Identified Species:
51.28
UniProt:
O75083
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75083
NP_005103.2
606
66194
S594
E
H
T
L
V
T
T
S
H
D
A
S
V
K
E
Chimpanzee
Pan troglodytes
XP_001158647
606
66166
S594
E
H
T
L
V
T
T
S
H
D
A
S
V
K
E
Rhesus Macaque
Macaca mulatta
XP_001097937
606
66149
S594
E
H
T
L
V
T
T
S
H
D
A
S
V
K
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88342
606
66388
S594
E
H
T
L
V
T
T
S
H
D
A
S
V
K
E
Rat
Rattus norvegicus
Q5RKI0
606
66163
S594
E
H
T
L
V
T
T
S
H
D
A
S
V
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508159
447
48280
D436
T
L
V
T
T
S
H
D
A
S
V
K
E
W
T
Chicken
Gallus gallus
O93277
609
66548
S596
E
H
T
L
V
T
T
S
H
D
A
S
V
K
E
Frog
Xenopus laevis
Q6PAX7
607
66151
S594
E
N
T
L
A
T
V
S
H
D
A
C
V
K
Q
Zebra Danio
Brachydanio rerio
NP_957333
606
66494
S594
P
N
T
L
V
T
T
S
H
D
A
C
I
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU68
608
66531
G595
N
N
T
V
I
S
T
G
Q
D
C
N
T
K
V
Honey Bee
Apis mellifera
XP_624088
602
66930
G589
E
E
T
L
I
S
V
G
Q
D
C
N
T
K
I
Nematode Worm
Caenorhab. elegans
Q11176
611
65305
A598
N
E
T
T
I
V
S
A
G
Q
D
S
N
I
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
G462
D
G
E
K
V
V
S
G
G
K
D
R
V
L
K
Baker's Yeast
Sacchar. cerevisiae
P46680
615
67307
A603
S
T
L
V
S
S
G
A
D
A
C
I
K
R
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
N.A.
N.A.
95.2
95.8
N.A.
67.1
88.1
80.4
74.9
N.A.
48.1
48.5
40
N.A.
Protein Similarity:
100
99.6
99.5
N.A.
N.A.
98.6
99
N.A.
70.9
94.5
90.1
87.6
N.A.
68.5
68.6
59
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
100
66.6
66.6
N.A.
26.6
33.3
13.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
100
80
86.6
N.A.
60
53.3
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.9
48.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
15
8
8
58
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
22
15
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
8
72
15
0
0
0
0
% D
% Glu:
58
15
8
0
0
0
0
0
0
0
0
0
8
0
43
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
22
15
0
0
0
0
0
0
% G
% His:
0
43
0
0
0
0
8
0
58
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
22
0
0
0
0
0
0
8
8
8
8
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
0
8
8
72
15
% K
% Leu:
0
8
8
65
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
22
0
0
0
0
0
0
0
0
0
15
8
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
15
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% R
% Ser:
8
0
0
0
8
29
15
58
0
8
0
50
0
0
0
% S
% Thr:
8
8
79
15
8
58
58
0
0
0
0
0
15
0
8
% T
% Val:
0
0
8
15
58
15
15
0
0
0
8
0
58
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _