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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR1 All Species: 43.33
Human Site: Y72 Identified Species: 73.33
UniProt: O75083 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75083 NP_005103.2 606 66194 Y72 K Y A P S G F Y I A S G D V S
Chimpanzee Pan troglodytes XP_001158647 606 66166 Y72 K Y A P S G F Y I A S G D V S
Rhesus Macaque Macaca mulatta XP_001097937 606 66149 Y72 K Y A P S G F Y I A S G D V S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88342 606 66388 Y72 K Y A P S G F Y I A S G D I S
Rat Rattus norvegicus Q5RKI0 606 66163 Y72 K Y A P S G F Y I A S G D I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508159 447 48280
Chicken Gallus gallus O93277 609 66548 Y74 K Y A P S G F Y I A S G D V S
Frog Xenopus laevis Q6PAX7 607 66151 Y72 R Y A P S G F Y I A S G D T S
Zebra Danio Brachydanio rerio NP_957333 606 66494 Y72 K Y C P S G F Y I A S G D V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VU68 608 66531 Y78 K Y S P S G F Y I A S G D A S
Honey Bee Apis mellifera XP_624088 602 66930 Y72 K Y S P S G F Y I A S G D Q S
Nematode Worm Caenorhab. elegans Q11176 611 65305 Y73 K T S P S G Y Y C A S G D V H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FLX9 473 52879
Baker's Yeast Sacchar. cerevisiae P46680 615 67307 E86 Q Y L C S G D E S G K V I V W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.1 N.A. N.A. 95.2 95.8 N.A. 67.1 88.1 80.4 74.9 N.A. 48.1 48.5 40 N.A.
Protein Similarity: 100 99.6 99.5 N.A. N.A. 98.6 99 N.A. 70.9 94.5 90.1 87.6 N.A. 68.5 68.6 59 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. 0 100 86.6 93.3 N.A. 86.6 86.6 66.6 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 0 100 93.3 93.3 N.A. 93.3 93.3 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.9 29.7 N.A.
Protein Similarity: N.A. N.A. N.A. 36.9 48.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 50 0 0 0 0 0 0 79 0 0 0 8 0 % A
% Cys: 0 0 8 8 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 79 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 72 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 86 0 0 0 8 0 79 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 72 0 0 0 8 15 0 % I
% Lys: 72 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 79 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 22 0 86 0 0 0 8 0 79 0 0 0 72 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 8 0 50 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 79 0 0 0 0 8 79 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _