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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD7
All Species:
25.76
Human Site:
Y561
Identified Species:
51.52
UniProt:
O75084
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75084
NP_003498.1
574
63620
Y561
L
Q
S
W
R
R
F
Y
H
R
L
S
H
S
S
Chimpanzee
Pan troglodytes
XP_519190
643
70814
L623
W
I
W
S
G
K
T
L
N
S
W
R
K
F
Y
Rhesus Macaque
Macaca mulatta
XP_001100283
574
63733
Y561
L
Q
S
W
R
R
F
Y
H
R
L
S
H
S
S
Dog
Lupus familis
XP_858911
609
67519
Y561
L
Q
S
W
R
R
F
Y
H
R
L
S
H
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61090
572
63798
Y559
L
Q
S
W
R
R
F
Y
H
R
L
S
H
S
S
Rat
Rattus norvegicus
Q08463
641
71009
L621
W
I
W
S
G
K
T
L
N
S
W
R
K
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519817
718
80521
Y705
L
H
S
W
R
K
F
Y
T
R
L
T
N
S
R
Chicken
Gallus gallus
O57329
567
62793
H555
Q
S
W
R
R
F
Y
H
R
L
S
T
G
S
K
Frog
Xenopus laevis
Q9PUK8
549
62101
Y536
L
Q
S
W
R
R
F
Y
H
R
L
S
N
G
S
Zebra Danio
Brachydanio rerio
NP_571214
559
63677
Y546
L
Q
S
W
R
R
F
Y
K
R
L
S
N
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
R562
S
K
T
M
V
S
W
R
N
F
V
E
R
L
Q
Honey Bee
Apis mellifera
XP_623523
571
64519
K550
S
F
W
V
W
S
S
K
T
L
T
S
W
R
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.3
98.9
92.2
N.A.
96.1
71.2
N.A.
64.6
87.4
84.8
80.3
N.A.
46.9
58.3
N.A.
N.A.
Protein Similarity:
100
79
99.3
92.7
N.A.
96.5
79.4
N.A.
69.9
90.2
89.5
87.6
N.A.
61.4
71.2
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
60
13.3
86.6
80
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
80
33.3
93.3
93.3
N.A.
33.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
9
0
0
0
9
59
0
0
9
0
0
0
17
0
% F
% Gly:
0
0
0
0
17
0
0
0
0
0
0
0
9
9
0
% G
% His:
0
9
0
0
0
0
0
9
42
0
0
0
34
0
0
% H
% Ile:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
25
0
9
9
0
0
0
17
0
9
% K
% Leu:
59
0
0
0
0
0
0
17
0
17
59
0
0
9
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
25
0
0
0
25
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
50
0
0
0
0
0
0
0
0
0
0
0
0
17
% Q
% Arg:
0
0
0
9
67
50
0
9
9
59
0
17
9
9
9
% R
% Ser:
17
9
59
17
0
17
9
0
0
17
9
59
0
59
42
% S
% Thr:
0
0
9
0
0
0
17
0
17
0
9
17
0
0
0
% T
% Val:
0
0
0
9
9
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
17
0
34
59
9
0
9
0
0
0
17
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
9
59
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _