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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEGF6
All Species:
6.97
Human Site:
S1425
Identified Species:
13.94
UniProt:
O75095
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75095
NP_001400.3
1541
161185
S1425
E
R
G
C
E
P
G
S
F
G
E
G
C
H
Q
Chimpanzee
Pan troglodytes
XP_513736
1499
156100
S1383
E
R
G
C
E
P
G
S
F
G
E
G
C
H
Q
Rhesus Macaque
Macaca mulatta
XP_001097941
1137
121871
N1028
C
S
L
S
S
S
E
N
P
Y
A
T
I
K
D
Dog
Lupus familis
XP_546739
1534
159127
F1421
Q
C
V
C
P
A
G
F
Y
G
Q
L
C
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80V70
1572
164704
E1463
G
F
R
G
Q
F
C
E
R
G
C
K
P
G
F
Rat
Rattus norvegicus
O88281
1574
165428
E1465
G
F
H
G
Q
F
C
E
K
G
C
E
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517394
825
86249
K716
K
S
C
T
C
F
N
K
A
T
C
N
P
I
T
Chicken
Gallus gallus
Frog
Xenopus laevis
P21783
2524
275106
I2159
K
K
A
R
K
P
S
I
K
G
N
G
C
K
E
Zebra Danio
Brachydanio rerio
P46530
2437
262289
G2146
K
K
T
R
K
P
G
G
K
G
V
G
G
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
Q2545
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
H
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
E1002
T
L
E
E
E
E
L
E
N
K
K
I
H
G
R
Sea Urchin
Strong. purpuratus
XP_781397
1496
158881
T1351
Q
F
S
C
P
A
G
T
Y
G
S
Y
C
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
27.8
73.3
N.A.
76.4
75.4
N.A.
36.2
N.A.
21
21.8
N.A.
21
N.A.
26.3
38.9
Protein Similarity:
100
94.4
37.3
80.4
N.A.
83.1
81.9
N.A.
42.2
N.A.
29.7
30.6
N.A.
29.4
N.A.
36.7
50.7
P-Site Identity:
100
100
0
26.6
N.A.
6.6
6.6
N.A.
0
N.A.
26.6
26.6
N.A.
13.3
N.A.
6.6
26.6
P-Site Similarity:
100
100
6.6
53.3
N.A.
13.3
13.3
N.A.
6.6
N.A.
53.3
46.6
N.A.
40
N.A.
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
17
0
0
9
0
9
0
0
0
0
% A
% Cys:
9
9
9
34
9
0
17
0
0
0
25
0
42
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% D
% Glu:
17
0
9
9
25
9
9
25
0
0
17
9
0
9
9
% E
% Phe:
0
25
0
0
0
25
0
9
17
0
0
0
0
0
9
% F
% Gly:
17
0
17
17
0
0
42
9
0
67
0
34
9
34
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
9
25
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
9
9
9
0
% I
% Lys:
25
17
0
0
17
0
0
9
25
9
9
9
0
25
9
% K
% Leu:
0
9
9
0
0
0
9
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
9
9
0
9
9
0
0
0
% N
% Pro:
0
0
0
0
17
34
0
0
9
0
0
0
17
0
0
% P
% Gln:
25
9
9
9
25
9
9
9
9
9
17
9
9
0
25
% Q
% Arg:
0
17
9
17
0
0
0
0
9
0
0
0
0
0
17
% R
% Ser:
0
17
9
9
9
9
9
17
0
0
9
0
9
0
9
% S
% Thr:
9
0
9
9
0
0
0
9
0
9
0
9
0
0
9
% T
% Val:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
17
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _