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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEGF6 All Species: 11.52
Human Site: S1528 Identified Species: 23.03
UniProt: O75095 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75095 NP_001400.3 1541 161185 S1528 S A G T L P A S S R P T S R S
Chimpanzee Pan troglodytes XP_513736 1499 156100 S1486 S A G T L P A S S R P T S R S
Rhesus Macaque Macaca mulatta XP_001097941 1137 121871 Q1125 D S S S S P K Q E D S G G S S
Dog Lupus familis XP_546739 1534 159127 G1522 V A S Q P A H G P A L R L S S
Cat Felis silvestris
Mouse Mus musculus Q80V70 1572 164704 P1560 T Q L S S I R P A P Q H S S S
Rat Rattus norvegicus O88281 1574 165428 P1562 T Q I S S S R P A P Q H P S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517394 825 86249 V813 D R H T G H C V C P A G W T G
Chicken Gallus gallus
Frog Xenopus laevis P21783 2524 275106 S2506 S D W S E G I S S P P T S M Q
Zebra Danio Brachydanio rerio P46530 2437 262289 S2421 S D W S E G I S S P P T S M Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07207 2703 288835 S2665 E S P G H W S S S S P R S N S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XWD6 1111 118785 S1099 P D P V T Q N S A N K K R A Q
Sea Urchin Strong. purpuratus XP_781397 1496 158881 C1454 D C S N G A T C D P R T G S C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 27.8 73.3 N.A. 76.4 75.4 N.A. 36.2 N.A. 21 21.8 N.A. 21 N.A. 26.3 38.9
Protein Similarity: 100 94.4 37.3 80.4 N.A. 83.1 81.9 N.A. 42.2 N.A. 29.7 30.6 N.A. 29.4 N.A. 36.7 50.7
P-Site Identity: 100 100 13.3 13.3 N.A. 13.3 6.6 N.A. 6.6 N.A. 40 40 N.A. 33.3 N.A. 6.6 6.6
P-Site Similarity: 100 100 26.6 13.3 N.A. 33.3 26.6 N.A. 6.6 N.A. 46.6 46.6 N.A. 46.6 N.A. 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 0 0 0 17 17 0 25 9 9 0 0 9 0 % A
% Cys: 0 9 0 0 0 0 9 9 9 0 0 0 0 0 9 % C
% Asp: 25 25 0 0 0 0 0 0 9 9 0 0 0 0 0 % D
% Glu: 9 0 0 0 17 0 0 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 17 9 17 17 0 9 0 0 0 17 17 0 9 % G
% His: 0 0 9 0 9 9 9 0 0 0 0 17 0 0 0 % H
% Ile: 0 0 9 0 0 9 17 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 9 9 0 0 0 % K
% Leu: 0 0 9 0 17 0 0 0 0 0 9 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % M
% Asn: 0 0 0 9 0 0 9 0 0 9 0 0 0 9 0 % N
% Pro: 9 0 17 0 9 25 0 17 9 50 42 0 9 0 0 % P
% Gln: 0 17 0 9 0 9 0 9 0 0 17 0 0 0 25 % Q
% Arg: 0 9 0 0 0 0 17 0 0 17 9 17 9 17 0 % R
% Ser: 34 17 25 42 25 9 9 50 42 9 9 0 50 42 59 % S
% Thr: 17 0 0 25 9 0 9 0 0 0 0 42 0 9 0 % T
% Val: 9 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 17 0 0 9 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _