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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEGF6
All Species:
12.42
Human Site:
T580
Identified Species:
24.85
UniProt:
O75095
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75095
NP_001400.3
1541
161185
T580
G
G
T
C
D
S
V
T
G
A
C
R
C
P
P
Chimpanzee
Pan troglodytes
XP_513736
1499
156100
E545
L
D
G
C
D
C
P
E
G
W
T
G
L
I
C
Rhesus Macaque
Macaca mulatta
XP_001097941
1137
121871
T303
C
H
C
S
P
G
Y
T
G
E
R
C
Q
D
E
Dog
Lupus familis
XP_546739
1534
159127
T546
G
G
T
C
D
P
V
T
G
A
C
R
C
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80V70
1572
164704
S582
G
G
T
C
D
P
V
S
G
A
C
R
C
P
P
Rat
Rattus norvegicus
O88281
1574
165428
L584
G
G
T
C
D
P
V
L
G
A
C
R
C
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517394
825
86249
Chicken
Gallus gallus
Frog
Xenopus laevis
P21783
2524
275106
L589
G
I
A
T
F
T
C
L
C
R
P
G
Y
T
G
Zebra Danio
Brachydanio rerio
P46530
2437
262289
D588
G
V
A
S
F
T
C
D
C
R
P
G
Y
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
E774
R
C
E
D
G
I
N
E
F
I
C
H
C
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
E278
H
G
A
L
C
E
N
E
C
S
V
G
F
F
G
Sea Urchin
Strong. purpuratus
XP_781397
1496
158881
T510
G
G
T
C
N
P
I
T
G
D
C
T
C
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
27.8
73.3
N.A.
76.4
75.4
N.A.
36.2
N.A.
21
21.8
N.A.
21
N.A.
26.3
38.9
Protein Similarity:
100
94.4
37.3
80.4
N.A.
83.1
81.9
N.A.
42.2
N.A.
29.7
30.6
N.A.
29.4
N.A.
36.7
50.7
P-Site Identity:
100
20
13.3
93.3
N.A.
86.6
86.6
N.A.
0
N.A.
6.6
6.6
N.A.
26.6
N.A.
6.6
60
P-Site Similarity:
100
20
13.3
93.3
N.A.
93.3
86.6
N.A.
0
N.A.
13.3
13.3
N.A.
26.6
N.A.
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
0
0
0
0
34
0
0
0
0
0
% A
% Cys:
9
9
9
50
9
9
17
0
25
0
50
9
50
0
9
% C
% Asp:
0
9
0
9
42
0
0
9
0
9
0
0
0
9
0
% D
% Glu:
0
0
9
0
0
9
0
25
0
9
0
0
0
0
9
% E
% Phe:
0
0
0
0
17
0
0
0
9
0
0
0
9
9
0
% F
% Gly:
59
50
9
0
9
9
0
0
59
0
0
34
0
0
25
% G
% His:
9
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
9
0
0
0
9
9
0
0
9
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
9
0
0
0
17
0
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
17
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
34
9
0
0
0
17
0
0
42
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
17
9
34
0
0
0
% R
% Ser:
0
0
0
17
0
9
0
9
0
9
0
0
0
0
0
% S
% Thr:
0
0
42
9
0
17
0
34
0
0
9
9
0
17
0
% T
% Val:
0
9
0
0
0
0
34
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _