KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEGF6
All Species:
13.33
Human Site:
T989
Identified Species:
26.67
UniProt:
O75095
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75095
NP_001400.3
1541
161185
T989
R
G
P
R
C
A
E
T
C
P
A
H
T
Y
G
Chimpanzee
Pan troglodytes
XP_513736
1499
156100
T947
R
G
P
R
C
A
E
T
C
P
A
H
T
Y
G
Rhesus Macaque
Macaca mulatta
XP_001097941
1137
121871
L655
L
P
G
F
T
G
A
L
C
N
E
V
C
P
S
Dog
Lupus familis
XP_546739
1534
159127
A955
Q
G
P
R
C
D
Q
A
C
P
A
H
T
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80V70
1572
164704
T991
W
G
P
H
C
A
Q
T
C
P
P
L
T
F
G
Rat
Rattus norvegicus
O88281
1574
165428
S993
W
G
P
R
C
A
Q
S
C
P
P
L
T
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517394
825
86249
F344
D
P
G
L
Y
G
R
F
C
H
L
A
C
P
K
Chicken
Gallus gallus
Frog
Xenopus laevis
P21783
2524
275106
T1076
N
G
G
K
C
W
Q
T
N
N
F
Y
R
C
E
Zebra Danio
Brachydanio rerio
P46530
2437
262289
L1113
Q
G
V
S
V
A
V
L
C
R
H
A
G
Q
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
D1451
K
W
K
G
K
R
C
D
I
Y
D
A
N
Y
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
Q630
T
K
G
V
S
C
D
Q
K
C
D
P
N
T
F
Sea Urchin
Strong. purpuratus
XP_781397
1496
158881
E917
T
G
Q
G
C
R
D
E
C
P
E
G
H
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
27.8
73.3
N.A.
76.4
75.4
N.A.
36.2
N.A.
21
21.8
N.A.
21
N.A.
26.3
38.9
Protein Similarity:
100
94.4
37.3
80.4
N.A.
83.1
81.9
N.A.
42.2
N.A.
29.7
30.6
N.A.
29.4
N.A.
36.7
50.7
P-Site Identity:
100
100
6.6
73.3
N.A.
60
60
N.A.
6.6
N.A.
20
20
N.A.
6.6
N.A.
0
33.3
P-Site Similarity:
100
100
6.6
86.6
N.A.
73.3
80
N.A.
6.6
N.A.
40
26.6
N.A.
13.3
N.A.
6.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
42
9
9
0
0
25
25
0
0
0
% A
% Cys:
0
0
0
0
59
9
9
0
75
9
0
0
17
9
9
% C
% Asp:
9
0
0
0
0
9
17
9
0
0
17
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
17
9
0
0
17
0
0
0
9
% E
% Phe:
0
0
0
9
0
0
0
9
0
0
9
0
0
25
9
% F
% Gly:
0
67
34
17
0
17
0
0
0
0
0
9
9
0
50
% G
% His:
0
0
0
9
0
0
0
0
0
9
9
25
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
9
9
9
9
9
0
0
0
9
0
0
0
0
0
9
% K
% Leu:
9
0
0
9
0
0
0
17
0
0
9
17
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
9
17
0
0
17
0
0
% N
% Pro:
0
17
42
0
0
0
0
0
0
50
17
9
0
17
9
% P
% Gln:
17
0
9
0
0
0
34
9
0
0
0
0
0
9
0
% Q
% Arg:
17
0
0
34
0
17
9
0
0
9
0
0
9
0
0
% R
% Ser:
0
0
0
9
9
0
0
9
0
0
0
0
0
0
9
% S
% Thr:
17
0
0
0
9
0
0
34
0
0
0
0
42
9
0
% T
% Val:
0
0
9
9
9
0
9
0
0
0
0
9
0
0
0
% V
% Trp:
17
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
9
0
9
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _