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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AOC2
All Species:
4.55
Human Site:
S638
Identified Species:
11.11
UniProt:
O75106
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75106
NP_001149.2
756
83673
S638
T
Q
R
K
E
E
E
S
Q
S
S
S
I
Y
H
Chimpanzee
Pan troglodytes
XP_511524
763
84549
P642
T
Q
R
K
E
E
E
P
S
S
S
S
V
F
N
Rhesus Macaque
Macaca mulatta
XP_001112259
763
84656
P642
T
Q
R
K
E
E
E
P
S
S
S
S
V
F
N
Dog
Lupus familis
XP_849207
756
83338
S638
T
R
R
K
E
E
E
S
Q
S
S
S
I
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q812C9
757
83564
P639
T
Q
R
K
E
A
E
P
H
S
S
S
I
Y
Y
Rat
Rattus norvegicus
O08590
763
84963
P642
T
Q
R
K
E
E
E
P
S
S
S
S
I
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425868
755
84769
P631
T
R
R
K
E
E
E
P
T
S
T
S
V
Y
N
Frog
Xenopus laevis
NP_001087039
759
85841
P634
T
K
R
K
D
E
E
P
Q
S
S
S
I
Y
N
Zebra Danio
Brachydanio rerio
NP_001013573
754
86293
Q630
T
K
H
K
D
E
E
Q
T
S
S
S
L
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H1H9
712
80120
L594
G
G
N
A
A
S
L
L
D
H
D
D
P
P
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.1
64.2
88.7
N.A.
80.8
62.9
N.A.
N.A.
54.6
49.7
43.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77
76.4
94.8
N.A.
88.1
74.1
N.A.
N.A.
70.9
67.8
62.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
66.6
86.6
N.A.
73.3
80
N.A.
N.A.
60
73.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
86.6
100
N.A.
80
86.6
N.A.
N.A.
86.6
93.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
20
0
0
0
10
0
10
10
0
0
0
% D
% Glu:
0
0
0
0
70
80
90
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
10
10
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% I
% Lys:
0
20
0
90
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
50
% N
% Pro:
0
0
0
0
0
0
0
60
0
0
0
0
10
10
0
% P
% Gln:
0
50
0
0
0
0
0
10
30
0
0
0
0
0
10
% Q
% Arg:
0
20
80
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
20
30
90
80
90
0
0
10
% S
% Thr:
90
0
0
0
0
0
0
0
20
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _