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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COBL
All Species:
8.48
Human Site:
S374
Identified Species:
26.67
UniProt:
O75128
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75128
NP_056013.2
1261
135617
S374
S
L
P
L
G
S
G
S
H
C
S
P
D
G
A
Chimpanzee
Pan troglodytes
XP_519099
1245
134112
S358
S
L
P
L
G
S
G
S
H
C
S
P
D
G
A
Rhesus Macaque
Macaca mulatta
XP_001082572
1610
173884
K754
G
G
R
Q
V
P
Q
K
P
P
R
G
T
A
R
Dog
Lupus familis
XP_849814
1567
166678
P561
K
S
A
T
V
S
L
P
S
G
P
S
S
P
C
Cat
Felis silvestris
Mouse
Mus musculus
Q5NBX1
1337
143846
S449
S
E
L
R
P
K
L
S
L
P
L
G
P
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513370
1145
127000
L291
K
P
F
V
S
N
T
L
P
S
D
M
P
K
K
Chicken
Gallus gallus
XP_419034
1325
144576
S375
T
L
P
L
G
R
G
S
R
C
S
I
G
D
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664846
606
65662
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
68.6
44.4
N.A.
62.9
N.A.
N.A.
22.3
44.2
N.A.
22.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
70
52.5
N.A.
73
N.A.
N.A.
37.5
58
N.A.
33.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
6.6
N.A.
20
N.A.
N.A.
0
53.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
6.6
N.A.
26.6
N.A.
N.A.
13.3
60
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
0
0
0
0
0
13
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
38
0
0
0
0
13
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
13
0
25
13
0
% D
% Glu:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
13
0
0
38
0
38
0
0
13
0
25
13
38
13
% G
% His:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% I
% Lys:
25
0
0
0
0
13
0
13
0
0
0
0
0
13
13
% K
% Leu:
0
38
13
38
0
0
25
13
13
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
13
38
0
13
13
0
13
25
25
13
25
25
13
0
% P
% Gln:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
13
13
0
13
0
0
13
0
13
0
0
0
13
% R
% Ser:
38
13
0
0
13
38
0
50
13
13
38
13
13
0
13
% S
% Thr:
13
0
0
13
0
0
13
0
0
0
0
0
13
0
0
% T
% Val:
0
0
0
13
25
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _