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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC5
All Species:
5.15
Human Site:
S1108
Identified Species:
12.59
UniProt:
O75140
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75140
NP_001007189.1
1572
177910
S1108
Q
S
M
D
R
G
N
S
Q
T
F
G
N
S
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852875
773
87442
D327
H
Y
I
N
R
N
F
D
R
T
G
Q
M
S
V
Cat
Felis silvestris
Mouse
Mus musculus
P61460
1527
173129
N1064
Q
P
M
D
R
G
N
N
Q
T
F
G
N
S
Q
Rat
Rattus norvegicus
NP_001100699
1456
164725
T1009
I
E
Q
A
F
P
S
T
G
S
G
D
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517877
828
93963
L382
H
A
V
P
L
F
K
L
H
N
R
C
G
P
R
Chicken
Gallus gallus
XP_415249
1571
177723
T1107
Q
S
A
E
R
G
S
T
Q
S
L
G
S
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691450
1590
178752
G1126
D
K
I
S
N
Q
P
G
E
R
T
S
A
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728620
1472
168864
A1026
A
T
D
A
A
A
A
A
G
V
A
A
R
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794020
1608
181354
Q1131
G
E
A
M
T
W
V
Q
R
S
F
S
D
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S9J6
2004
222187
A1284
D
P
S
V
V
I
A
A
E
L
E
T
L
P
L
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
48
N.A.
91.7
87.4
N.A.
49.5
89.1
N.A.
75.5
N.A.
35.7
N.A.
N.A.
32.4
Protein Similarity:
100
N.A.
N.A.
48.6
N.A.
93.8
89.6
N.A.
50.9
94
N.A.
84.5
N.A.
53.7
N.A.
N.A.
48.6
P-Site Identity:
100
N.A.
N.A.
20
N.A.
86.6
6.6
N.A.
0
53.3
N.A.
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
40
N.A.
93.3
26.6
N.A.
20
86.6
N.A.
20
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
20
20
10
10
20
20
0
0
10
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
20
0
10
20
0
0
0
10
0
0
0
10
10
10
10
% D
% Glu:
0
20
0
10
0
0
0
0
20
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
10
10
10
0
0
0
30
0
0
0
0
% F
% Gly:
10
0
0
0
0
30
0
10
20
0
20
30
20
0
0
% G
% His:
20
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
20
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
10
0
10
10
0
10
0
10
% L
% Met:
0
0
20
10
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
10
10
20
10
0
10
0
0
20
0
0
% N
% Pro:
0
20
0
10
0
10
10
0
0
0
0
0
0
20
0
% P
% Gln:
30
0
10
0
0
10
0
10
30
0
0
10
0
0
30
% Q
% Arg:
0
0
0
0
40
0
0
0
20
10
10
0
10
0
10
% R
% Ser:
0
20
10
10
0
0
20
10
0
30
0
20
10
50
20
% S
% Thr:
0
10
0
0
10
0
0
20
0
30
10
10
0
0
0
% T
% Val:
0
0
10
10
10
0
10
0
0
10
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _