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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0652 All Species: 21.21
Human Site: S262 Identified Species: 42.42
UniProt: O75143 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75143 NP_001136145.1 517 56572 S262 S F S T S P P S Q L S S S R L
Chimpanzee Pan troglodytes A5A6N3 474 52050 Y242 G E D T G V I Y P S V E D S Q
Rhesus Macaque Macaca mulatta XP_001111885 517 56440 S262 S F S T S P P S Q L S S S R L
Dog Lupus familis XP_540752 642 70289 S262 S F S T S P P S Q C V F T V T
Cat Felis silvestris
Mouse Mus musculus Q91YI1 516 56422 S261 S F S T S P P S Q L S S S R L
Rat Rattus norvegicus XP_342466 516 56441 S261 S F S T S P P S Q L S S S R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517376 328 35088 Q96 Y P S V E D S Q E V C T T S F
Chicken Gallus gallus XP_421116 549 59853 H294 V M G L A F S H Q L S S S R L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SYE0 503 54718 S262 S F S T S P P S Q L Y S S R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHR6 523 56908 K276 R R F I D I E K P L R P G A F
Honey Bee Apis mellifera XP_623782 410 45626 Q178 Y K H V R V G Q L C T P V G T
Nematode Worm Caenorhab. elegans P34379 443 49782 K211 E E I D D G E K T V V D E N I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 99 78.9 N.A. 93.6 94.7 N.A. 57.4 87.4 N.A. 73.5 N.A. 25 33.2 22.6 N.A.
Protein Similarity: 100 91.3 99.4 79.1 N.A. 95.7 96.1 N.A. 59.5 90.5 N.A. 82.9 N.A. 40.5 50.4 43.5 N.A.
P-Site Identity: 100 6.6 100 60 N.A. 100 100 N.A. 6.6 46.6 N.A. 93.3 N.A. 6.6 0 0 N.A.
P-Site Similarity: 100 6.6 100 66.6 N.A. 100 100 N.A. 33.3 53.3 N.A. 93.3 N.A. 6.6 6.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 17 9 0 0 0 0 % C
% Asp: 0 0 9 9 17 9 0 0 0 0 0 9 9 0 0 % D
% Glu: 9 17 0 0 9 0 17 0 9 0 0 9 9 0 0 % E
% Phe: 0 50 9 0 0 9 0 0 0 0 0 9 0 0 17 % F
% Gly: 9 0 9 0 9 9 9 0 0 0 0 0 9 9 0 % G
% His: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 0 9 9 0 0 0 0 0 0 0 9 % I
% Lys: 0 9 0 0 0 0 0 17 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 0 0 0 0 9 59 0 0 0 0 50 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 9 0 0 0 50 50 0 17 0 0 17 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 17 59 0 0 0 0 0 9 % Q
% Arg: 9 9 0 0 9 0 0 0 0 0 9 0 0 50 0 % R
% Ser: 50 0 59 0 50 0 17 50 0 9 42 50 50 17 0 % S
% Thr: 0 0 0 59 0 0 0 0 9 0 9 9 17 0 17 % T
% Val: 9 0 0 17 0 17 0 0 0 17 25 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _