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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICOSLG
All Species:
6.06
Human Site:
S293
Identified Species:
19.05
UniProt:
O75144
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75144
NP_056074.1
302
33349
S293
Y
A
G
A
W
A
V
S
P
E
T
E
L
T
G
Chimpanzee
Pan troglodytes
XP_531578
309
34288
S293
Y
A
G
A
W
A
V
S
P
E
T
E
L
T
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544918
289
32276
R280
P
C
R
W
R
A
A
R
P
E
Q
A
L
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHJ8
322
35941
T313
R
S
Y
T
G
P
K
T
V
Q
L
E
L
T
D
Rat
Rattus norvegicus
Q7TPB4
316
34056
A285
C
E
E
E
N
A
G
A
E
D
Q
D
G
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512359
488
54824
M478
I
P
I
S
A
I
T
M
Q
P
K
M
P
N
E
Chicken
Gallus gallus
NP_990415
296
33137
F287
W
L
W
R
R
R
S
F
Q
L
V
S
Y
T
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074091
300
32705
E290
E
E
A
R
V
L
E
E
A
K
S
E
A
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.1
N.A.
53.9
N.A.
44.4
26.8
N.A.
26.4
33.4
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.4
N.A.
65.2
N.A.
56.8
42
N.A.
37.9
53.6
N.A.
42.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
26.6
N.A.
20
13.3
N.A.
0
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
26.6
N.A.
40
33.3
N.A.
6.6
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
13
25
13
50
13
13
13
0
0
13
13
0
13
% A
% Cys:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
13
0
13
0
13
25
% D
% Glu:
13
25
13
13
0
0
13
13
13
38
0
50
0
0
25
% E
% Phe:
0
0
0
0
0
0
0
13
0
0
0
0
0
13
0
% F
% Gly:
0
0
25
0
13
0
13
0
0
0
0
0
13
0
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
13
0
0
13
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
13
0
0
13
13
0
0
0
0
% K
% Leu:
0
13
0
0
0
13
0
0
0
13
13
0
50
0
0
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
0
0
0
0
13
0
% N
% Pro:
13
13
0
0
0
13
0
0
38
13
0
0
13
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
25
13
25
0
0
0
0
% Q
% Arg:
13
0
13
25
25
13
0
13
0
0
0
0
0
0
0
% R
% Ser:
0
13
0
13
0
0
13
25
0
0
13
13
0
0
0
% S
% Thr:
0
0
0
13
0
0
13
13
0
0
25
0
0
63
13
% T
% Val:
0
0
0
0
13
0
25
0
13
0
13
0
0
0
0
% V
% Trp:
13
0
13
13
25
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
0
13
0
0
0
0
0
0
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _