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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPFIA3
All Species:
9.7
Human Site:
S666
Identified Species:
23.7
UniProt:
O75145
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75145
NP_003651.1
1194
133496
S666
L
T
T
S
T
L
A
S
P
S
P
P
S
S
G
Chimpanzee
Pan troglodytes
XP_508612
1335
150142
S825
P
A
S
S
L
A
S
S
S
P
P
G
S
G
R
Rhesus Macaque
Macaca mulatta
XP_001104868
1195
134548
S639
L
T
A
L
S
L
A
S
A
S
P
P
L
S
G
Dog
Lupus familis
XP_533206
1261
142404
P712
P
T
S
V
L
T
G
P
S
P
P
H
S
G
R
Cat
Felis silvestris
Mouse
Mus musculus
P60469
1043
116262
K546
D
K
T
N
H
V
S
K
E
E
A
G
V
P
R
Rat
Rattus norvegicus
Q91Z79
1192
133411
S665
L
T
T
S
T
L
A
S
P
S
P
P
S
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505810
1257
143115
L713
A
S
V
T
A
S
S
L
A
S
S
S
P
P
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A9C3W3
786
88912
Q303
P
L
T
A
A
I
R
Q
S
Q
Q
N
L
Y
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21049
1139
130316
Q644
M
G
M
P
S
G
M
Q
G
G
M
Q
G
G
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
K461
K
K
T
H
S
E
S
K
T
I
T
D
N
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56
61
61.6
N.A.
85.7
97.7
N.A.
60
N.A.
N.A.
25.2
N.A.
N.A.
N.A.
41.5
N.A.
Protein Similarity:
100
69
74
75.3
N.A.
86.1
98.4
N.A.
73.2
N.A.
N.A.
39.3
N.A.
N.A.
N.A.
57.5
N.A.
P-Site Identity:
100
26.6
66.6
20
N.A.
6.6
100
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
40
73.3
26.6
N.A.
26.6
100
N.A.
26.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
20
10
30
0
20
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
10
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
10
0
10
10
0
20
10
30
30
% G
% His:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
20
0
0
0
0
0
20
0
0
0
0
0
0
0
% K
% Leu:
30
10
0
10
20
30
0
10
0
0
0
0
20
0
10
% L
% Met:
10
0
10
0
0
0
10
0
0
0
10
0
0
0
10
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
30
0
0
10
0
0
0
10
20
20
50
30
10
20
0
% P
% Gln:
0
0
0
0
0
0
0
20
0
10
10
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
30
% R
% Ser:
0
10
20
30
30
10
40
40
30
40
10
10
40
30
10
% S
% Thr:
0
40
50
10
20
10
0
0
10
0
10
0
0
0
0
% T
% Val:
0
0
10
10
0
10
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _