KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1R
All Species:
6.97
Human Site:
S1027
Identified Species:
11.79
UniProt:
O75146
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75146
NP_003950.1
1068
119388
S1027
E
E
V
A
I
R
P
S
T
A
P
R
S
V
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
Q995
L
E
L
E
N
E
L
Q
K
E
R
Q
K
L
G
Dog
Lupus familis
XP_543376
1149
127844
S1108
E
E
D
P
S
R
P
S
A
A
T
R
S
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKY5
1068
119467
S1027
E
E
E
P
S
R
P
S
P
A
P
R
S
G
A
Rat
Rattus norvegicus
Q9EPY0
536
62613
E497
K
E
R
R
R
L
K
E
S
F
E
N
Y
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
A1020
D
E
E
L
S
R
P
A
P
S
P
R
R
G
I
Chicken
Gallus gallus
NP_001025828
976
110183
L930
A
E
K
S
S
R
N
L
G
K
L
Q
E
C
S
Frog
Xenopus laevis
NP_001086615
1066
120922
A1027
N
D
G
E
P
I
P
A
Q
K
P
G
I
L
K
Zebra Danio
Brachydanio rerio
NP_001077034
1065
119979
E1023
E
I
A
G
V
P
L
E
Q
L
S
E
D
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648597
1124
128381
S1068
A
T
V
K
D
C
N
S
Q
L
E
Q
Q
S
E
Honey Bee
Apis mellifera
XP_394258
927
105031
K888
G
L
R
L
H
Q
A
K
R
L
E
M
E
A
Q
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
K888
E
E
M
E
S
Q
V
K
M
L
E
L
E
Q
S
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
K930
E
L
E
S
K
L
E
K
E
R
V
K
L
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
T928
L
D
F
T
S
E
H
T
L
K
T
A
E
M
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
50.4
82.2
N.A.
91
20.5
N.A.
82.3
71.9
72.7
61.8
N.A.
24.6
36.9
33.3
38.8
Protein Similarity:
100
N.A.
68.4
86.8
N.A.
95.4
32.7
N.A.
90.6
82.3
85.9
78.7
N.A.
44
54.4
50.2
56.8
P-Site Identity:
100
N.A.
6.6
53.3
N.A.
60
6.6
N.A.
33.3
13.3
13.3
6.6
N.A.
13.3
0
13.3
6.6
P-Site Similarity:
100
N.A.
26.6
53.3
N.A.
60
20
N.A.
53.3
33.3
33.3
13.3
N.A.
20
6.6
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
8
0
0
8
15
8
22
0
8
0
15
15
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
15
8
0
8
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
43
58
22
22
0
15
8
15
8
8
29
8
29
0
22
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
8
8
0
0
0
0
8
0
0
8
0
22
15
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
8
0
0
0
0
0
0
8
0
8
% I
% Lys:
8
0
8
8
8
0
8
22
8
22
0
8
8
0
8
% K
% Leu:
15
15
8
15
0
15
15
8
8
29
8
8
8
15
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
8
0
8
0
% M
% Asn:
8
0
0
0
8
0
15
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
15
8
8
36
0
15
0
29
0
0
0
0
% P
% Gln:
0
0
0
0
0
15
0
8
22
0
0
22
8
8
8
% Q
% Arg:
0
0
15
8
8
36
0
0
8
8
8
29
8
8
8
% R
% Ser:
0
0
0
15
43
0
0
29
8
8
8
0
22
8
15
% S
% Thr:
0
8
0
8
0
0
0
8
8
0
15
0
0
0
8
% T
% Val:
0
0
15
0
8
0
8
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _