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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1R
All Species:
8.48
Human Site:
S441
Identified Species:
14.36
UniProt:
O75146
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75146
NP_003950.1
1068
119388
S441
E
E
A
E
R
K
A
S
A
T
E
A
R
Y
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
Q462
S
E
I
E
R
K
A
Q
A
N
E
Q
R
Y
S
Dog
Lupus familis
XP_543376
1149
127844
S522
E
E
A
E
K
K
A
S
V
T
E
A
R
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKY5
1068
119467
S441
E
E
A
E
R
K
A
S
A
T
E
A
R
Y
S
Rat
Rattus norvegicus
Q9EPY0
536
62613
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
N434
V
E
A
E
R
K
A
N
I
T
E
V
R
Y
T
Chicken
Gallus gallus
NP_001025828
976
110183
R397
E
G
E
V
E
E
Q
R
K
Q
K
Q
K
A
L
Frog
Xenopus laevis
NP_001086615
1066
120922
Q442
V
E
T
E
K
K
I
Q
A
T
E
L
R
Y
T
Zebra Danio
Brachydanio rerio
NP_001077034
1065
119979
Q447
V
E
T
E
K
R
A
Q
A
T
E
L
R
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648597
1124
128381
N414
K
L
S
S
E
K
F
N
K
L
K
T
L
Y
T
Honey Bee
Apis mellifera
XP_394258
927
105031
I362
V
L
T
D
H
Q
R
I
V
E
E
L
Q
I
H
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
R362
R
I
E
Q
Y
E
N
R
L
L
Q
M
Q
G
E
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
F403
E
E
V
N
Q
L
K
F
E
L
E
R
T
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
Q386
V
Q
Q
L
Q
Q
Q
Q
A
Q
Q
E
L
F
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
50.4
82.2
N.A.
91
20.5
N.A.
82.3
71.9
72.7
61.8
N.A.
24.6
36.9
33.3
38.8
Protein Similarity:
100
N.A.
68.4
86.8
N.A.
95.4
32.7
N.A.
90.6
82.3
85.9
78.7
N.A.
44
54.4
50.2
56.8
P-Site Identity:
100
N.A.
60
80
N.A.
93.3
0
N.A.
66.6
6.6
53.3
60
N.A.
13.3
6.6
0
20
P-Site Similarity:
100
N.A.
66.6
86.6
N.A.
100
0
N.A.
73.3
26.6
60
73.3
N.A.
40
33.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
29
0
0
0
43
0
43
0
0
22
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
36
58
15
50
15
15
0
0
8
8
65
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
8
0
0
0
8
8
8
0
0
0
0
8
0
% I
% Lys:
8
0
0
0
22
50
8
0
15
0
15
0
8
8
8
% K
% Leu:
0
15
0
8
0
8
0
0
8
22
0
22
15
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
15
0
8
0
0
0
0
15
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
8
15
15
15
29
0
15
15
15
15
0
15
% Q
% Arg:
8
0
0
0
29
8
8
15
0
0
0
8
50
0
0
% R
% Ser:
8
0
8
8
0
0
0
22
0
0
0
0
0
0
15
% S
% Thr:
0
0
22
0
0
0
0
0
0
43
0
8
8
0
22
% T
% Val:
36
0
8
8
0
0
0
0
15
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
58
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _