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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1R
All Species:
23.33
Human Site:
S541
Identified Species:
39.49
UniProt:
O75146
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75146
NP_003950.1
1068
119388
S541
A
L
S
H
T
E
Q
S
K
S
E
L
S
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
E548
E
L
A
T
S
Q
R
E
L
Q
V
L
Q
G
S
Dog
Lupus familis
XP_543376
1149
127844
S622
A
L
T
R
T
E
Q
S
G
L
E
L
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKY5
1068
119467
S541
A
L
S
R
T
E
Q
S
G
S
E
L
S
S
R
Rat
Rattus norvegicus
Q9EPY0
536
62613
N53
E
Q
V
L
S
D
P
N
L
V
I
R
K
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
S534
T
L
S
H
S
E
Q
S
G
S
E
L
N
T
R
Chicken
Gallus gallus
NP_001025828
976
110183
S479
Q
L
T
V
T
Q
Q
S
Q
E
E
V
A
R
V
Frog
Xenopus laevis
NP_001086615
1066
120922
T542
S
L
S
N
T
E
E
T
K
S
Q
L
N
S
T
Zebra Danio
Brachydanio rerio
NP_001077034
1065
119979
T547
S
L
Q
T
S
E
M
T
G
V
Q
M
N
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648597
1124
128381
T542
L
N
G
N
L
N
D
T
L
E
K
L
S
N
A
Honey Bee
Apis mellifera
XP_394258
927
105031
Q444
L
E
E
L
I
Q
G
Q
A
I
T
E
Q
E
R
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
I444
A
L
T
K
L
G
D
I
Q
K
Q
L
E
A
S
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
D485
E
R
F
K
K
M
K
D
V
Y
N
K
L
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
K477
Q
L
D
V
W
E
R
K
Y
E
S
L
A
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
50.4
82.2
N.A.
91
20.5
N.A.
82.3
71.9
72.7
61.8
N.A.
24.6
36.9
33.3
38.8
Protein Similarity:
100
N.A.
68.4
86.8
N.A.
95.4
32.7
N.A.
90.6
82.3
85.9
78.7
N.A.
44
54.4
50.2
56.8
P-Site Identity:
100
N.A.
13.3
73.3
N.A.
86.6
0
N.A.
66.6
33.3
53.3
20
N.A.
13.3
6.6
20
0
P-Site Similarity:
100
N.A.
40
80
N.A.
86.6
26.6
N.A.
86.6
66.6
93.3
60
N.A.
40
13.3
46.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
0
8
0
0
0
0
0
8
0
0
0
15
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
15
8
0
0
0
0
0
0
0
% D
% Glu:
22
8
8
0
0
50
8
8
0
22
36
8
8
8
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
8
0
29
0
0
0
0
8
0
% G
% His:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
0
8
8
0
0
0
0
% I
% Lys:
0
0
0
15
8
0
8
8
15
8
8
8
8
8
8
% K
% Leu:
15
72
0
15
15
0
0
0
22
8
0
65
8
0
8
% L
% Met:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
15
0
8
0
8
0
0
8
0
22
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
15
8
8
0
0
22
36
8
15
8
22
0
15
0
0
% Q
% Arg:
0
8
0
15
0
0
15
0
0
0
0
8
0
22
36
% R
% Ser:
15
0
29
0
29
0
0
36
0
29
8
0
29
36
22
% S
% Thr:
8
0
22
15
36
0
0
22
0
0
8
0
0
8
8
% T
% Val:
0
0
8
15
0
0
0
0
8
15
8
8
0
0
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _