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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1R
All Species:
21.82
Human Site:
S653
Identified Species:
36.92
UniProt:
O75146
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75146
NP_003950.1
1068
119388
S653
L
H
L
R
C
T
S
S
P
D
Y
L
V
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
L642
I
Q
D
A
L
N
Q
L
E
E
P
P
L
I
S
Dog
Lupus familis
XP_543376
1149
127844
S734
L
H
L
R
C
T
S
S
P
D
Y
L
V
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKY5
1068
119467
S653
L
H
L
R
C
T
S
S
P
D
Y
L
V
S
R
Rat
Rattus norvegicus
Q9EPY0
536
62613
L147
K
D
D
F
I
K
E
L
R
V
K
D
S
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
S646
L
H
V
R
C
T
C
S
P
D
Y
L
V
S
R
Chicken
Gallus gallus
NP_001025828
976
110183
V575
L
L
S
V
H
S
L
V
Q
E
K
E
L
Q
L
Frog
Xenopus laevis
NP_001086615
1066
120922
S654
L
H
I
R
C
T
S
S
P
D
Y
L
V
C
R
Zebra Danio
Brachydanio rerio
NP_001077034
1065
119979
S659
I
H
I
S
C
S
S
S
P
D
Y
L
I
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648597
1124
128381
N673
Q
L
Q
L
T
L
N
N
L
E
Q
N
E
S
A
Honey Bee
Apis mellifera
XP_394258
927
105031
N538
T
L
H
E
L
L
L
N
C
I
F
K
A
E
D
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
L538
N
K
I
R
L
A
E
L
E
V
A
K
E
S
G
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
P579
I
T
Q
Q
M
D
D
P
Q
F
A
S
A
T
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
I573
T
Q
D
K
M
N
P
I
L
D
A
I
L
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
50.4
82.2
N.A.
91
20.5
N.A.
82.3
71.9
72.7
61.8
N.A.
24.6
36.9
33.3
38.8
Protein Similarity:
100
N.A.
68.4
86.8
N.A.
95.4
32.7
N.A.
90.6
82.3
85.9
78.7
N.A.
44
54.4
50.2
56.8
P-Site Identity:
100
N.A.
0
100
N.A.
100
0
N.A.
86.6
6.6
86.6
66.6
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
N.A.
20
100
N.A.
100
0
N.A.
93.3
26.6
93.3
93.3
N.A.
26.6
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
0
0
22
0
15
0
8
% A
% Cys:
0
0
0
0
43
0
8
0
8
0
0
0
0
8
8
% C
% Asp:
0
8
22
0
0
8
8
0
0
50
0
8
0
0
8
% D
% Glu:
0
0
0
8
0
0
15
0
15
22
0
8
15
15
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
43
8
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
22
0
22
0
8
0
0
8
0
8
0
8
8
8
0
% I
% Lys:
8
8
0
8
0
8
0
0
0
0
15
15
0
0
0
% K
% Leu:
43
22
22
8
22
15
15
22
15
0
0
43
22
8
15
% L
% Met:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
15
8
15
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
8
43
0
8
8
0
0
0
% P
% Gln:
8
15
15
8
0
0
8
0
15
0
8
0
0
8
0
% Q
% Arg:
0
0
0
43
0
0
0
0
8
0
0
0
0
0
43
% R
% Ser:
0
0
8
8
0
15
36
43
0
0
0
8
8
50
15
% S
% Thr:
15
8
0
0
8
36
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
8
8
0
0
0
8
0
15
0
0
36
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _