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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1R
All Species:
5.76
Human Site:
T839
Identified Species:
9.74
UniProt:
O75146
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75146
NP_003950.1
1068
119388
T839
K
A
I
R
L
L
V
T
T
S
T
S
L
Q
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
K807
R
I
E
E
M
L
S
K
S
R
A
G
D
T
G
Dog
Lupus familis
XP_543376
1149
127844
T920
K
A
I
R
L
L
V
T
T
S
T
S
L
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKY5
1068
119467
M839
K
A
I
R
L
L
V
M
T
S
T
S
L
Q
K
Rat
Rattus norvegicus
Q9EPY0
536
62613
Q310
S
L
R
K
D
L
R
Q
A
E
A
L
R
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
M832
K
A
I
R
L
L
V
M
T
S
T
S
L
Q
K
Chicken
Gallus gallus
NP_001025828
976
110183
T742
G
E
L
K
D
K
Q
T
L
G
H
A
E
L
G
Frog
Xenopus laevis
NP_001086615
1066
120922
I840
K
A
I
R
L
L
V
I
T
S
T
D
L
Q
K
Zebra Danio
Brachydanio rerio
NP_001077034
1065
119979
N831
E
V
N
E
R
I
L
N
S
C
T
D
L
M
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648597
1124
128381
K879
E
K
L
I
E
K
I
K
A
S
F
E
Q
K
I
Honey Bee
Apis mellifera
XP_394258
927
105031
M701
V
E
T
E
L
L
S
M
D
K
A
I
E
E
A
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
Q701
D
A
I
R
R
A
V
Q
E
I
E
A
I
Q
R
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
R743
E
E
M
L
K
R
S
R
E
A
D
T
G
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
N741
N
I
Q
S
V
K
S
N
K
E
T
N
P
H
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
50.4
82.2
N.A.
91
20.5
N.A.
82.3
71.9
72.7
61.8
N.A.
24.6
36.9
33.3
38.8
Protein Similarity:
100
N.A.
68.4
86.8
N.A.
95.4
32.7
N.A.
90.6
82.3
85.9
78.7
N.A.
44
54.4
50.2
56.8
P-Site Identity:
100
N.A.
6.6
100
N.A.
93.3
6.6
N.A.
93.3
6.6
86.6
13.3
N.A.
6.6
13.3
33.3
6.6
P-Site Similarity:
100
N.A.
26.6
100
N.A.
93.3
20
N.A.
93.3
26.6
86.6
46.6
N.A.
33.3
20
53.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
0
0
0
8
0
0
15
8
22
15
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
0
15
0
0
0
8
0
8
15
8
0
0
% D
% Glu:
22
22
8
22
8
0
0
0
15
15
8
8
15
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
8
0
8
8
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
15
43
8
0
8
8
8
0
8
0
8
8
0
8
% I
% Lys:
36
8
0
15
8
22
0
15
8
8
0
0
0
8
43
% K
% Leu:
0
8
15
8
43
58
8
0
8
0
0
8
43
8
0
% L
% Met:
0
0
8
0
8
0
0
22
0
0
0
0
0
8
0
% M
% Asn:
8
0
8
0
0
0
0
15
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
8
0
0
0
8
15
0
0
0
0
8
43
8
% Q
% Arg:
8
0
8
43
15
8
8
8
0
8
0
0
8
0
15
% R
% Ser:
8
0
0
8
0
0
29
0
15
43
0
29
0
0
8
% S
% Thr:
0
0
8
0
0
0
0
22
36
0
50
8
0
15
0
% T
% Val:
8
8
0
0
8
0
43
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _