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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIP1R All Species: 13.33
Human Site: T993 Identified Species: 22.56
UniProt: O75146 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75146 NP_003950.1 1068 119388 T993 R V L E L E K T L E A E R M R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001109894 1037 116235 E961 I S G K S Q I E E T D N M D F
Dog Lupus familis XP_543376 1149 127844 T1074 R V L E L E K T L E A E R V R
Cat Felis silvestris
Mouse Mus musculus Q9JKY5 1068 119467 T993 R V L E L E K T L E A E R V R
Rat Rattus norvegicus Q9EPY0 536 62613 Q464 A D R E S P E Q P F V V L N K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506915 1061 119171 T986 K V L E L E K T L E N E R M K
Chicken Gallus gallus NP_001025828 976 110183 G896 D R V V L Q T G K Y E E L I V
Frog Xenopus laevis NP_001086615 1066 120922 M994 K V L E L E N M L Q N E R M H
Zebra Danio Brachydanio rerio NP_001077034 1065 119979 E985 S L I K L K K E E M E S Q V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648597 1124 128381 V1033 Q M V I A S K V K A E R N S Q
Honey Bee Apis mellifera XP_394258 927 105031 Q855 E A S R D V T Q A T G S V V A
Nematode Worm Caenorhab. elegans Q02328 927 104410 V855 T A Q V V A A V K N G Q T T L
Sea Urchin Strong. purpuratus XP_785542 970 108923 G897 G A Q M I E E G D S P D F T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P33338 968 108893 D895 H C S K D V T D A C R S L G N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 50.4 82.2 N.A. 91 20.5 N.A. 82.3 71.9 72.7 61.8 N.A. 24.6 36.9 33.3 38.8
Protein Similarity: 100 N.A. 68.4 86.8 N.A. 95.4 32.7 N.A. 90.6 82.3 85.9 78.7 N.A. 44 54.4 50.2 56.8
P-Site Identity: 100 N.A. 0 93.3 N.A. 93.3 6.6 N.A. 80 13.3 60 13.3 N.A. 6.6 0 0 6.6
P-Site Similarity: 100 N.A. 13.3 100 N.A. 100 20 N.A. 93.3 33.3 73.3 60 N.A. 33.3 6.6 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 22 0 0 8 8 8 0 15 8 22 0 0 0 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 8 8 0 0 15 0 0 8 8 0 8 8 0 8 0 % D
% Glu: 8 0 0 43 0 43 15 15 15 29 22 43 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 8 % F
% Gly: 8 0 8 0 0 0 0 15 0 0 15 0 0 8 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 8 8 8 0 8 0 0 0 0 0 0 8 0 % I
% Lys: 15 0 0 22 0 8 43 0 22 0 0 0 0 0 29 % K
% Leu: 0 8 36 0 50 0 0 0 36 0 0 0 22 0 8 % L
% Met: 0 8 0 8 0 0 0 8 0 8 0 0 8 22 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 8 15 8 8 8 8 % N
% Pro: 0 0 0 0 0 8 0 0 8 0 8 0 0 0 0 % P
% Gln: 8 0 15 0 0 15 0 15 0 8 0 8 8 0 8 % Q
% Arg: 22 8 8 8 0 0 0 0 0 0 8 8 36 0 22 % R
% Ser: 8 8 15 0 15 8 0 0 0 8 0 22 0 8 0 % S
% Thr: 8 0 0 0 0 0 22 29 0 15 0 0 8 15 0 % T
% Val: 0 36 15 15 8 15 0 15 0 0 8 8 8 29 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _