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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1R
All Species:
27.27
Human Site:
Y126
Identified Species:
46.15
UniProt:
O75146
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75146
NP_003950.1
1068
119388
Y126
W
G
H
L
H
D
R
Y
G
Q
L
V
N
V
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
Y135
W
G
H
L
S
E
G
Y
G
Q
L
C
S
I
Y
Dog
Lupus familis
XP_543376
1149
127844
Y207
W
G
H
L
H
D
R
Y
G
Q
L
V
N
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKY5
1068
119467
Y126
W
G
H
L
R
D
Q
Y
G
H
L
V
N
I
Y
Rat
Rattus norvegicus
Q9EPY0
536
62613
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
Y119
W
G
H
L
H
D
R
Y
G
Q
L
V
N
V
Y
Chicken
Gallus gallus
NP_001025828
976
110183
Y126
W
G
H
L
H
D
R
Y
G
Q
L
V
S
I
Y
Frog
Xenopus laevis
NP_001086615
1066
120922
Y126
W
G
H
M
H
D
R
Y
G
Q
L
V
T
I
Y
Zebra Danio
Brachydanio rerio
NP_001077034
1065
119979
Y128
N
T
R
D
R
H
G
Y
A
L
L
V
S
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648597
1124
128381
F131
F
H
D
K
N
R
M
F
P
G
T
L
N
I
S
Honey Bee
Apis mellifera
XP_394258
927
105031
D98
R
Y
R
G
R
L
E
D
L
G
K
L
W
Q
H
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
Q98
R
Y
V
N
R
F
T
Q
L
S
Q
F
W
K
H
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
K136
H
F
H
D
G
Y
G
K
L
N
A
A
Y
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
K116
Y
V
R
Y
L
V
L
K
L
D
F
H
A
H
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
50.4
82.2
N.A.
91
20.5
N.A.
82.3
71.9
72.7
61.8
N.A.
24.6
36.9
33.3
38.8
Protein Similarity:
100
N.A.
68.4
86.8
N.A.
95.4
32.7
N.A.
90.6
82.3
85.9
78.7
N.A.
44
54.4
50.2
56.8
P-Site Identity:
100
N.A.
60
100
N.A.
73.3
0
N.A.
100
86.6
80
20
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
N.A.
80
100
N.A.
86.6
0
N.A.
100
100
93.3
40
N.A.
40
13.3
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
0
8
15
0
43
0
8
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
0
8
0
8
0
0
8
8
0
0
0
% F
% Gly:
0
50
0
8
8
0
22
0
50
15
0
0
0
0
0
% G
% His:
8
8
58
0
36
8
0
0
0
8
0
8
0
8
29
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
36
0
% I
% Lys:
0
0
0
8
0
0
0
15
0
0
8
0
0
8
0
% K
% Leu:
0
0
0
43
8
8
8
0
29
8
58
15
0
8
0
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
8
0
0
0
0
8
0
0
36
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
8
0
43
8
0
0
8
0
% Q
% Arg:
15
0
22
0
29
8
36
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
0
8
0
0
22
0
15
% S
% Thr:
0
8
0
0
0
0
8
0
0
0
8
0
8
0
0
% T
% Val:
0
8
8
0
0
8
0
0
0
0
0
50
0
22
0
% V
% Trp:
50
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% W
% Tyr:
8
15
0
8
0
8
0
58
0
0
0
0
8
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _