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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1R
All Species:
35.15
Human Site:
Y227
Identified Species:
59.49
UniProt:
O75146
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75146
NP_003950.1
1068
119388
Y227
I
Q
D
C
S
H
L
Y
H
Y
T
V
K
L
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
Y236
I
L
D
C
S
H
L
Y
D
Y
T
V
K
L
L
Dog
Lupus familis
XP_543376
1149
127844
Y308
I
Q
D
C
S
H
L
Y
H
Y
T
V
K
L
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKY5
1068
119467
Y227
I
Q
D
C
S
H
L
Y
H
Y
T
V
K
L
M
Rat
Rattus norvegicus
Q9EPY0
536
62613
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
Y220
I
Q
D
C
S
P
L
Y
H
Y
T
V
K
L
M
Chicken
Gallus gallus
NP_001025828
976
110183
Y227
I
Q
D
C
S
H
L
Y
H
Y
A
V
K
L
M
Frog
Xenopus laevis
NP_001086615
1066
120922
Y227
I
Q
D
C
S
H
L
Y
H
Y
T
V
K
L
M
Zebra Danio
Brachydanio rerio
NP_001077034
1065
119979
Y229
I
Q
D
C
S
H
L
Y
H
Y
T
V
K
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648597
1124
128381
F234
V
S
G
H
R
D
R
F
H
G
L
F
L
K
L
Honey Bee
Apis mellifera
XP_394258
927
105031
A198
V
S
G
Q
C
R
L
A
P
L
I
P
C
V
L
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
S198
P
Q
G
Q
C
M
L
S
P
L
I
I
A
I
L
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
Y237
I
L
D
S
G
Q
L
Y
D
F
S
V
R
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
G217
R
Q
L
N
D
A
E
G
D
A
A
L
Q
P
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
50.4
82.2
N.A.
91
20.5
N.A.
82.3
71.9
72.7
61.8
N.A.
24.6
36.9
33.3
38.8
Protein Similarity:
100
N.A.
68.4
86.8
N.A.
95.4
32.7
N.A.
90.6
82.3
85.9
78.7
N.A.
44
54.4
50.2
56.8
P-Site Identity:
100
N.A.
86.6
93.3
N.A.
93.3
0
N.A.
86.6
86.6
93.3
100
N.A.
13.3
13.3
20
46.6
P-Site Similarity:
100
N.A.
86.6
100
N.A.
100
0
N.A.
93.3
93.3
100
100
N.A.
26.6
26.6
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
8
15
0
8
0
0
% A
% Cys:
0
0
0
58
15
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
65
0
8
8
0
0
22
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
0
8
0
0
0
% F
% Gly:
0
0
22
0
8
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
8
0
50
0
0
58
0
0
0
0
0
0
% H
% Ile:
65
0
0
0
0
0
0
0
0
0
15
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
58
8
0
% K
% Leu:
0
15
8
0
0
0
79
0
0
15
8
8
8
65
58
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
36
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
8
0
0
15
0
0
8
0
8
0
% P
% Gln:
0
65
0
15
0
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
0
8
8
8
0
0
0
0
0
8
0
0
% R
% Ser:
0
15
0
8
58
0
0
8
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% T
% Val:
15
0
0
0
0
0
0
0
0
0
0
65
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
58
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _