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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF40 All Species: 6.97
Human Site: S114 Identified Species: 10.22
UniProt: O75150 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75150 NP_055586.1 1001 113678 S114 A L L R C H E S Q G E L S S A
Chimpanzee Pan troglodytes Q2TLZ5 664 76145
Rhesus Macaque Macaca mulatta XP_001102375 1094 123413 G207 A L L R C H E G Q G E L S S A
Dog Lupus familis XP_848895 1001 113606 S114 A L L R H H E S Q G E L S S G
Cat Felis silvestris
Mouse Mus musculus Q3U319 1001 113949 N114 A L L Q C Y E N Q R E L S S G
Rat Rattus norvegicus Q8CJB9 1002 113822 Q115 L L Q C Y E N Q R E L S S S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521737 913 103647 P87 G T Q E C P E P D G A P V A E
Chicken Gallus gallus Q5ZLS3 984 114789 I106 Q F D E N I R I I L K R F D L
Frog Xenopus laevis Q6DFL0 524 61335
Zebra Danio Brachydanio rerio Q6NZW0 581 66777
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP9 1044 119041 D111 R V L L Q R F D A E T A D E L
Honey Bee Apis mellifera XP_625025 866 101052 N88 S W D K E E L N D K L A N R V
Nematode Worm Caenorhab. elegans P34537 837 97425 E74 R I A E L E K E N E R S K R R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXD6 878 99700 S90 S L K T V H K S W E K L T A S
Baker's Yeast Sacchar. cerevisiae Q07457 700 80674
Red Bread Mold Neurospora crassa Q7S304 707 80536
Conservation
Percent
Protein Identity: 100 20.9 90 96.4 N.A. 92.5 92.5 N.A. 70.5 58.9 20.6 20.3 N.A. 43 47.5 25 N.A.
Protein Similarity: 100 36.9 90.4 97.5 N.A. 95.1 95.2 N.A. 76.5 74 34 35.1 N.A. 60.5 62.2 46.3 N.A.
P-Site Identity: 100 0 93.3 86.6 N.A. 66.6 20 N.A. 20 0 0 0 N.A. 6.6 0 0 N.A.
P-Site Similarity: 100 0 93.3 86.6 N.A. 86.6 26.6 N.A. 26.6 6.6 0 0 N.A. 13.3 26.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.6 21.2 23.2
Protein Similarity: N.A. N.A. N.A. 44.2 39.6 40.4
P-Site Identity: N.A. N.A. N.A. 26.6 0 0
P-Site Similarity: N.A. N.A. N.A. 66.6 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 7 0 0 0 0 0 7 0 7 13 0 13 13 % A
% Cys: 0 0 0 7 25 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 0 0 0 0 7 13 0 0 0 7 7 0 % D
% Glu: 0 0 0 19 7 19 32 7 0 25 25 0 0 7 7 % E
% Phe: 0 7 0 0 0 0 7 0 0 0 0 0 7 0 0 % F
% Gly: 7 0 0 0 0 0 0 7 0 25 0 0 0 0 19 % G
% His: 0 0 0 0 7 25 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 7 0 7 7 0 0 0 0 0 0 % I
% Lys: 0 0 7 7 0 0 13 0 0 7 13 0 7 0 0 % K
% Leu: 7 38 32 7 7 0 7 0 0 7 13 32 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 7 13 7 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 7 0 7 0 0 0 7 0 0 0 % P
% Gln: 7 0 13 7 7 0 0 7 25 0 0 0 0 0 0 % Q
% Arg: 13 0 0 19 0 7 7 0 7 7 7 7 0 13 7 % R
% Ser: 13 0 0 0 0 0 0 19 0 0 0 13 32 32 7 % S
% Thr: 0 7 0 7 0 0 0 0 0 0 7 0 7 0 0 % T
% Val: 0 7 0 0 7 0 0 0 0 0 0 0 7 0 7 % V
% Trp: 0 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _