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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF40 All Species: 13.03
Human Site: S120 Identified Species: 19.11
UniProt: O75150 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75150 NP_055586.1 1001 113678 S120 E S Q G E L S S A P E A P G T
Chimpanzee Pan troglodytes Q2TLZ5 664 76145
Rhesus Macaque Macaca mulatta XP_001102375 1094 123413 S213 E G Q G E L S S A P E A P G T
Dog Lupus familis XP_848895 1001 113606 S120 E S Q G E L S S G T D A P G T
Cat Felis silvestris
Mouse Mus musculus Q3U319 1001 113949 S120 E N Q R E L S S G T E V P G C
Rat Rattus norvegicus Q8CJB9 1002 113822 S121 N Q R E L S S S G T E V P G C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521737 913 103647 A93 E P D G A P V A E A G T P E R
Chicken Gallus gallus Q5ZLS3 984 114789 D112 R I I L K R F D L D Q G L G D
Frog Xenopus laevis Q6DFL0 524 61335
Zebra Danio Brachydanio rerio Q6NZW0 581 66777
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP9 1044 119041 E117 F D A E T A D E L E N R N E N
Honey Bee Apis mellifera XP_625025 866 101052 R94 L N D K L A N R V Q V S K R A
Nematode Worm Caenorhab. elegans P34537 837 97425 R80 K E N E R S K R R Q Q T D E S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXD6 878 99700 A96 K S W E K L T A S V E S C S V
Baker's Yeast Sacchar. cerevisiae Q07457 700 80674
Red Bread Mold Neurospora crassa Q7S304 707 80536
Conservation
Percent
Protein Identity: 100 20.9 90 96.4 N.A. 92.5 92.5 N.A. 70.5 58.9 20.6 20.3 N.A. 43 47.5 25 N.A.
Protein Similarity: 100 36.9 90.4 97.5 N.A. 95.1 95.2 N.A. 76.5 74 34 35.1 N.A. 60.5 62.2 46.3 N.A.
P-Site Identity: 100 0 93.3 80 N.A. 60 33.3 N.A. 20 6.6 0 0 N.A. 0 0 0 N.A.
P-Site Similarity: 100 0 93.3 86.6 N.A. 66.6 40 N.A. 26.6 20 0 0 N.A. 0 20 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.6 21.2 23.2
Protein Similarity: N.A. N.A. N.A. 44.2 39.6 40.4
P-Site Identity: N.A. N.A. N.A. 20 0 0
P-Site Similarity: N.A. N.A. N.A. 60 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 13 0 13 13 7 0 19 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 13 % C
% Asp: 0 7 13 0 0 0 7 7 0 7 7 0 7 0 7 % D
% Glu: 32 7 0 25 25 0 0 7 7 7 32 0 0 19 0 % E
% Phe: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 25 0 0 0 0 19 0 7 7 0 38 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 13 0 0 7 13 0 7 0 0 0 0 0 7 0 0 % K
% Leu: 7 0 0 7 13 32 0 0 13 0 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 13 7 0 0 0 7 0 0 0 7 0 7 0 7 % N
% Pro: 0 7 0 0 0 7 0 0 0 13 0 0 38 0 0 % P
% Gln: 0 7 25 0 0 0 0 0 0 13 13 0 0 0 0 % Q
% Arg: 7 0 7 7 7 7 0 13 7 0 0 7 0 7 7 % R
% Ser: 0 19 0 0 0 13 32 32 7 0 0 13 0 7 7 % S
% Thr: 0 0 0 0 7 0 7 0 0 19 0 13 0 0 19 % T
% Val: 0 0 0 0 0 0 7 0 7 7 7 13 0 0 7 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _