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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF40 All Species: 18.79
Human Site: S42 Identified Species: 27.56
UniProt: O75150 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75150 NP_055586.1 1001 113678 S42 P I R L G G I S S T E E M D L
Chimpanzee Pan troglodytes Q2TLZ5 664 76145
Rhesus Macaque Macaca mulatta XP_001102375 1094 123413 S135 P I R L G G I S S T E E M D L
Dog Lupus familis XP_848895 1001 113606 S42 P I R L G G I S S T E E M D L
Cat Felis silvestris
Mouse Mus musculus Q3U319 1001 113949 S42 P I R L G G I S S T E E M D S
Rat Rattus norvegicus Q8CJB9 1002 113822 S42 P I R L G G I S S T E E M D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521737 913 103647 D42 E K R Q A T D D A T L L I V N
Chicken Gallus gallus Q5ZLS3 984 114789 S42 I K L G G V S S T E E L D I R
Frog Xenopus laevis Q6DFL0 524 61335
Zebra Danio Brachydanio rerio Q6NZW0 581 66777
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP9 1044 119041 M45 P V S T L E E M D I K V L E F
Honey Bee Apis mellifera XP_625025 866 101052 Q43 V V N R Y W N Q L N E D I R I
Nematode Worm Caenorhab. elegans P34537 837 97425 I29 G Q Q K R R K I Q F E P V R M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXD6 878 99700 A43 S E D K L D T A V L Q F Q N L
Baker's Yeast Sacchar. cerevisiae Q07457 700 80674
Red Bread Mold Neurospora crassa Q7S304 707 80536
Conservation
Percent
Protein Identity: 100 20.9 90 96.4 N.A. 92.5 92.5 N.A. 70.5 58.9 20.6 20.3 N.A. 43 47.5 25 N.A.
Protein Similarity: 100 36.9 90.4 97.5 N.A. 95.1 95.2 N.A. 76.5 74 34 35.1 N.A. 60.5 62.2 46.3 N.A.
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. 13.3 20 0 0 N.A. 6.6 6.6 6.6 N.A.
P-Site Similarity: 100 0 100 100 N.A. 93.3 93.3 N.A. 26.6 26.6 0 0 N.A. 33.3 33.3 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.6 21.2 23.2
Protein Similarity: N.A. N.A. N.A. 44.2 39.6 40.4
P-Site Identity: N.A. N.A. N.A. 6.6 0 0
P-Site Similarity: N.A. N.A. N.A. 26.6 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 7 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 7 7 7 7 0 0 7 7 32 0 % D
% Glu: 7 7 0 0 0 7 7 0 0 7 50 32 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 7 % F
% Gly: 7 0 0 7 38 32 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 32 0 0 0 0 32 7 0 7 0 0 13 7 7 % I
% Lys: 0 13 0 13 0 0 7 0 0 0 7 0 0 0 0 % K
% Leu: 0 0 7 32 13 0 0 0 7 7 7 13 7 0 25 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 32 0 7 % M
% Asn: 0 0 7 0 0 0 7 0 0 7 0 0 0 7 7 % N
% Pro: 38 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 7 7 7 0 0 0 7 7 0 7 0 7 0 0 % Q
% Arg: 0 0 38 7 7 7 0 0 0 0 0 0 0 13 7 % R
% Ser: 7 0 7 0 0 0 7 38 32 0 0 0 0 0 13 % S
% Thr: 0 0 0 7 0 7 7 0 7 38 0 0 0 0 0 % T
% Val: 7 13 0 0 0 7 0 0 7 0 0 7 7 7 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _