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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF40
All Species:
10.3
Human Site:
S621
Identified Species:
15.11
UniProt:
O75150
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75150
NP_055586.1
1001
113678
S621
L
R
E
R
E
G
P
S
L
G
P
P
P
V
A
Chimpanzee
Pan troglodytes
Q2TLZ5
664
76145
S362
K
C
T
S
K
S
P
S
T
H
K
D
L
M
E
Rhesus Macaque
Macaca mulatta
XP_001102375
1094
123413
G714
L
R
E
R
E
G
P
G
L
G
P
P
P
V
A
Dog
Lupus familis
XP_848895
1001
113606
G621
L
R
E
R
E
G
P
G
L
G
P
P
S
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3U319
1001
113949
S621
L
R
E
R
E
G
P
S
L
G
P
P
P
A
A
Rat
Rattus norvegicus
Q8CJB9
1002
113822
S622
L
R
E
R
E
G
P
S
L
G
P
P
P
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521737
913
103647
R565
V
K
A
E
E
S
K
R
K
E
S
D
L
L
K
Chicken
Gallus gallus
Q5ZLS3
984
114789
K604
E
K
E
R
E
R
E
K
Q
K
Q
K
E
S
E
Frog
Xenopus laevis
Q6DFL0
524
61335
E222
W
E
D
V
S
P
S
E
D
D
T
T
K
I
T
Zebra Danio
Brachydanio rerio
Q6NZW0
581
66777
K278
A
L
E
E
D
T
S
K
L
N
A
L
Q
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRP9
1044
119041
S640
P
G
P
G
N
S
T
S
S
A
T
N
S
V
P
Honey Bee
Apis mellifera
XP_625025
866
101052
D549
G
V
G
K
E
Q
R
D
K
V
Q
L
M
A
A
Nematode Worm
Caenorhab. elegans
P34537
837
97425
L535
I
R
Q
E
Y
E
S
L
C
K
E
V
K
R
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXD6
878
99700
A560
A
K
E
Q
E
Y
R
A
W
A
H
V
Q
S
L
Baker's Yeast
Sacchar. cerevisiae
Q07457
700
80674
L398
L
L
S
K
I
A
I
L
E
A
E
K
S
K
T
Red Bread Mold
Neurospora crassa
Q7S304
707
80536
V405
S
A
H
L
N
E
L
V
E
A
M
T
D
R
V
Conservation
Percent
Protein Identity:
100
20.9
90
96.4
N.A.
92.5
92.5
N.A.
70.5
58.9
20.6
20.3
N.A.
43
47.5
25
N.A.
Protein Similarity:
100
36.9
90.4
97.5
N.A.
95.1
95.2
N.A.
76.5
74
34
35.1
N.A.
60.5
62.2
46.3
N.A.
P-Site Identity:
100
13.3
93.3
86.6
N.A.
93.3
93.3
N.A.
6.6
20
0
13.3
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
26.6
93.3
86.6
N.A.
93.3
93.3
N.A.
26.6
26.6
13.3
26.6
N.A.
13.3
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
21.2
23.2
Protein Similarity:
N.A.
N.A.
N.A.
44.2
39.6
40.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
7
7
0
0
7
0
7
0
25
7
0
0
19
38
% A
% Cys:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
0
0
7
7
7
0
13
7
0
0
% D
% Glu:
7
7
50
19
57
13
7
7
13
7
13
0
7
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
7
7
0
32
0
13
0
32
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
7
7
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
7
0
0
0
0
0
0
7
0
% I
% Lys:
7
19
0
13
7
0
7
13
13
13
7
13
13
7
7
% K
% Leu:
38
13
0
7
0
0
7
13
38
0
0
13
13
13
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
7
7
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
7
0
7
0
0
7
38
0
0
0
32
32
25
0
7
% P
% Gln:
0
0
7
7
0
7
0
0
7
0
13
0
13
0
0
% Q
% Arg:
0
38
0
38
0
7
13
7
0
0
0
0
0
13
7
% R
% Ser:
7
0
7
7
7
19
19
32
7
0
7
0
19
13
0
% S
% Thr:
0
0
7
0
0
7
7
0
7
0
13
13
0
0
13
% T
% Val:
7
7
0
7
0
0
0
7
0
7
0
13
0
25
7
% V
% Trp:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _