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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF40 All Species: 33.03
Human Site: S841 Identified Species: 48.44
UniProt: O75150 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75150 NP_055586.1 1001 113678 S841 K E R A L Q G S L G G V E K E
Chimpanzee Pan troglodytes Q2TLZ5 664 76145 K527 L T M D M K V K E D Q I R E L
Rhesus Macaque Macaca mulatta XP_001102375 1094 123413 S934 K E R A L Q G S L G G V E K E
Dog Lupus familis XP_848895 1001 113606 S841 K E R A L Q G S L G G V E K E
Cat Felis silvestris
Mouse Mus musculus Q3U319 1001 113949 S841 K E R A L Q G S L G G V E K E
Rat Rattus norvegicus Q8CJB9 1002 113822 S842 K E R A L Q G S L G G V E K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521737 913 103647 S759 K E R V L Q G S L G G V E K E
Chicken Gallus gallus Q5ZLS3 984 114789 S824 K E H L L Q S S I G T G E K E
Frog Xenopus laevis Q6DFL0 524 61335 L387 L K S I Q A E L F E K N K E L
Zebra Danio Brachydanio rerio Q6NZW0 581 66777 K443 S E L F E R N K E L A D L R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP9 1044 119041 T883 K E R S L Q A T V A S I E K E
Honey Bee Apis mellifera XP_625025 866 101052 A719 E L A L R Q Q A M E M H K R K
Nematode Worm Caenorhab. elegans P34537 837 97425 E700 Q H R K N I Q E V G M S R D E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXD6 878 99700 S733 D K Y Q K S V S L E N L Q K K
Baker's Yeast Sacchar. cerevisiae Q07457 700 80674 T563 K I I D L N N T S T K L K R S
Red Bread Mold Neurospora crassa Q7S304 707 80536 K570 T I V T E S K K L E S L S S E
Conservation
Percent
Protein Identity: 100 20.9 90 96.4 N.A. 92.5 92.5 N.A. 70.5 58.9 20.6 20.3 N.A. 43 47.5 25 N.A.
Protein Similarity: 100 36.9 90.4 97.5 N.A. 95.1 95.2 N.A. 76.5 74 34 35.1 N.A. 60.5 62.2 46.3 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 93.3 60 0 6.6 N.A. 53.3 6.6 20 N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 93.3 66.6 20 20 N.A. 80 46.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.6 21.2 23.2
Protein Similarity: N.A. N.A. N.A. 44.2 39.6 40.4
P-Site Identity: N.A. N.A. N.A. 20 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. 46.6 40 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 32 0 7 7 7 0 7 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 13 0 0 0 0 0 7 0 7 0 7 0 % D
% Glu: 7 57 0 0 13 0 7 7 13 25 0 0 50 13 63 % E
% Phe: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 38 0 0 50 38 7 0 0 0 % G
% His: 0 7 7 0 0 0 0 0 0 0 0 7 0 0 7 % H
% Ile: 0 13 7 7 0 7 0 0 7 0 0 13 0 0 0 % I
% Lys: 57 13 0 7 7 7 7 19 0 0 13 0 19 57 13 % K
% Leu: 13 7 7 13 57 0 0 7 50 7 0 19 7 0 13 % L
% Met: 0 0 7 0 7 0 0 0 7 0 13 0 0 0 0 % M
% Asn: 0 0 0 0 7 7 13 0 0 0 7 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 7 7 57 13 0 0 0 7 0 7 0 0 % Q
% Arg: 0 0 50 0 7 7 0 0 0 0 0 0 13 19 0 % R
% Ser: 7 0 7 7 0 13 7 50 7 0 13 7 7 7 7 % S
% Thr: 7 7 0 7 0 0 0 13 0 7 7 0 0 0 0 % T
% Val: 0 0 7 7 0 0 13 0 13 0 0 38 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _