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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF40 All Species: 20.91
Human Site: T278 Identified Species: 30.67
UniProt: O75150 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75150 NP_055586.1 1001 113678 T278 K V L E M E T T V E D L Q W D
Chimpanzee Pan troglodytes Q2TLZ5 664 76145 Y66 W L F I R S V Y D S F R Y Q G
Rhesus Macaque Macaca mulatta XP_001102375 1094 123413 T371 K V L E M E T T V E D L Q W D
Dog Lupus familis XP_848895 1001 113606 T278 K V L E M E T T V E D L Q W D
Cat Felis silvestris
Mouse Mus musculus Q3U319 1001 113949 T278 K V L E M E T T V E D L Q W D
Rat Rattus norvegicus Q8CJB9 1002 113822 T279 K V L E M E T T V E D L Q W D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521737 913 103647 N251 G R A L S P S N A H L L R G P
Chicken Gallus gallus Q5ZLS3 984 114789 M270 R V S V L E T M I D D L Q W N
Frog Xenopus laevis Q6DFL0 524 61335
Zebra Danio Brachydanio rerio Q6NZW0 581 66777
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP9 1044 119041 Q275 E N A E L K N Q I D E L Q Y D
Honey Bee Apis mellifera XP_625025 866 101052 D252 V S Q T K L E D L Q R E L E E
Nematode Worm Caenorhab. elegans P34537 837 97425 E238 E N R V Q E L E H Q L E D A R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXD6 878 99700 D254 R I R G E L E D E V V E L Q Q
Baker's Yeast Sacchar. cerevisiae Q07457 700 80674 T102 E I A Q G D E T L I V Q R S D
Red Bread Mold Neurospora crassa Q7S304 707 80536 L109 G S L K S I A L K P V D S N W
Conservation
Percent
Protein Identity: 100 20.9 90 96.4 N.A. 92.5 92.5 N.A. 70.5 58.9 20.6 20.3 N.A. 43 47.5 25 N.A.
Protein Similarity: 100 36.9 90.4 97.5 N.A. 95.1 95.2 N.A. 76.5 74 34 35.1 N.A. 60.5 62.2 46.3 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 6.6 46.6 0 0 N.A. 26.6 0 6.6 N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 20 80 0 0 N.A. 73.3 20 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.6 21.2 23.2
Protein Similarity: N.A. N.A. N.A. 44.2 39.6 40.4
P-Site Identity: N.A. N.A. N.A. 0 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 53.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 0 0 7 0 7 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 13 7 13 38 7 7 0 44 % D
% Glu: 19 0 0 38 7 44 19 7 7 32 7 19 0 7 7 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 13 0 0 7 7 0 0 0 0 0 0 0 0 7 7 % G
% His: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % H
% Ile: 0 13 0 7 0 7 0 0 13 7 0 0 0 0 0 % I
% Lys: 32 0 0 7 7 7 0 0 7 0 0 0 0 0 0 % K
% Leu: 0 7 38 7 13 13 7 7 13 0 13 50 13 0 0 % L
% Met: 0 0 0 0 32 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 0 0 7 7 0 0 0 0 0 7 7 % N
% Pro: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 7 % P
% Gln: 0 0 7 7 7 0 0 7 0 13 0 7 44 13 7 % Q
% Arg: 13 7 13 0 7 0 0 0 0 0 7 7 13 0 7 % R
% Ser: 0 13 7 0 13 7 7 0 0 7 0 0 7 7 0 % S
% Thr: 0 0 0 7 0 0 38 38 0 0 0 0 0 0 0 % T
% Val: 7 38 0 13 0 0 7 0 32 7 19 0 0 0 0 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 0 0 38 7 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _