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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF40 All Species: 29.09
Human Site: T385 Identified Species: 42.67
UniProt: O75150 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75150 NP_055586.1 1001 113678 T385 P E E V V R E T G E Y R M L Q
Chimpanzee Pan troglodytes Q2TLZ5 664 76145 D149 D L K N F H V D L C R P F A A
Rhesus Macaque Macaca mulatta XP_001102375 1094 123413 T478 P E E V V R E T G E Y R M L Q
Dog Lupus familis XP_848895 1001 113606 T385 P E E V V R E T G E Y R M L Q
Cat Felis silvestris
Mouse Mus musculus Q3U319 1001 113949 T385 P E E V V R E T G E Y R M L Q
Rat Rattus norvegicus Q8CJB9 1002 113822 T386 P E E V V R E T G E Y R M L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521737 913 103647 F341 Y R L L Q A Q F S L L Y N E S
Chicken Gallus gallus Q5ZLS3 984 114789 T378 V E E A V K E T P E Y R C M Q
Frog Xenopus laevis Q6DFL0 524 61335 P9 S Q S S D P S P R L V E S P L
Zebra Danio Brachydanio rerio Q6NZW0 581 66777 G65 G L G C D G I G D W E S R E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP9 1044 119041 T394 P E S V I V E T T E Y K C L Q
Honey Bee Apis mellifera XP_625025 866 101052 S336 D A R Q Q L Q S S K N A H L R
Nematode Worm Caenorhab. elegans P34537 837 97425 A321 R D E Q E S I A S R R L Q D L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXD6 878 99700 S345 M S N L Q N K S K S V R C I S
Baker's Yeast Sacchar. cerevisiae Q07457 700 80674 T185 Y D R D E S F T I K R V F K E
Red Bread Mold Neurospora crassa Q7S304 707 80536 L192 L Q A E N A T L S E Q Y D T A
Conservation
Percent
Protein Identity: 100 20.9 90 96.4 N.A. 92.5 92.5 N.A. 70.5 58.9 20.6 20.3 N.A. 43 47.5 25 N.A.
Protein Similarity: 100 36.9 90.4 97.5 N.A. 95.1 95.2 N.A. 76.5 74 34 35.1 N.A. 60.5 62.2 46.3 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 0 60 0 0 N.A. 60 6.6 6.6 N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 13.3 73.3 6.6 6.6 N.A. 73.3 33.3 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.6 21.2 23.2
Protein Similarity: N.A. N.A. N.A. 44.2 39.6 40.4
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 7 0 13 0 7 0 0 0 7 0 7 13 % A
% Cys: 0 0 0 7 0 0 0 0 0 7 0 0 19 0 0 % C
% Asp: 13 13 0 7 13 0 0 7 7 0 0 0 7 7 0 % D
% Glu: 0 44 44 7 13 0 44 0 0 50 7 7 0 13 13 % E
% Phe: 0 0 0 0 7 0 7 7 0 0 0 0 13 0 0 % F
% Gly: 7 0 7 0 0 7 0 7 32 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 7 0 13 0 7 0 0 0 0 7 0 % I
% Lys: 0 0 7 0 0 7 7 0 7 13 0 7 0 7 0 % K
% Leu: 7 13 7 13 0 7 0 7 7 13 7 7 0 44 13 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 32 7 0 % M
% Asn: 0 0 7 7 7 7 0 0 0 0 7 0 7 0 0 % N
% Pro: 38 0 0 0 0 7 0 7 7 0 0 7 0 7 0 % P
% Gln: 0 13 0 13 19 0 13 0 0 0 7 0 7 0 44 % Q
% Arg: 7 7 13 0 0 32 0 0 7 7 19 44 7 0 7 % R
% Ser: 7 7 13 7 0 13 7 13 25 7 0 7 7 0 13 % S
% Thr: 0 0 0 0 0 0 7 50 7 0 0 0 0 7 0 % T
% Val: 7 0 0 38 38 7 7 0 0 0 13 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 13 0 0 0 0 0 0 0 0 0 44 13 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _