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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF40 All Species: 12.73
Human Site: T557 Identified Species: 18.67
UniProt: O75150 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75150 NP_055586.1 1001 113678 T557 G G P G P V S T P D N R K E M
Chimpanzee Pan troglodytes Q2TLZ5 664 76145 V303 K R L N N D L V G S T E N L L
Rhesus Macaque Macaca mulatta XP_001102375 1094 123413 T650 G G P G P V S T P D N R K E M
Dog Lupus familis XP_848895 1001 113606 A557 G G P G P V T A P D G R K E M
Cat Felis silvestris
Mouse Mus musculus Q3U319 1001 113949 T557 S G P G P G G T P D C K K E M
Rat Rattus norvegicus Q8CJB9 1002 113822 T558 S G P G P G G T P D S K K E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521737 913 103647 E506 E A P A S E E E P A S T S A P
Chicken Gallus gallus Q5ZLS3 984 114789 D541 P E I K Q E P D D P S S Q V S
Frog Xenopus laevis Q6DFL0 524 61335 L163 L Q G K A R V L V S N D H D I
Zebra Danio Brachydanio rerio Q6NZW0 581 66777 D219 P V R D I G T D K L Y K Q K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP9 1044 119041 N569 V K E E N S N N V S A S G Q T
Honey Bee Apis mellifera XP_625025 866 101052 K490 G E G N K D I K K E T I K T E
Nematode Worm Caenorhab. elegans P34537 837 97425 K475 R S M N R S L K S E K I R L R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXD6 878 99700 E501 V L C R K T K E Y E A L Q L R
Baker's Yeast Sacchar. cerevisiae Q07457 700 80674 S339 A E L S E I N S S F L S K F Q
Red Bread Mold Neurospora crassa Q7S304 707 80536 A346 A E R T S Y R A T L E Q E A Q
Conservation
Percent
Protein Identity: 100 20.9 90 96.4 N.A. 92.5 92.5 N.A. 70.5 58.9 20.6 20.3 N.A. 43 47.5 25 N.A.
Protein Similarity: 100 36.9 90.4 97.5 N.A. 95.1 95.2 N.A. 76.5 74 34 35.1 N.A. 60.5 62.2 46.3 N.A.
P-Site Identity: 100 0 100 80 N.A. 66.6 60 N.A. 13.3 0 6.6 0 N.A. 0 13.3 0 N.A.
P-Site Similarity: 100 6.6 100 86.6 N.A. 73.3 80 N.A. 20 13.3 20 26.6 N.A. 13.3 20 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.6 21.2 23.2
Protein Similarity: N.A. N.A. N.A. 44.2 39.6 40.4
P-Site Identity: N.A. N.A. N.A. 0 6.6 0
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 7 0 7 7 0 0 13 0 7 13 0 0 13 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 0 0 7 0 13 0 13 7 32 0 7 0 7 0 % D
% Glu: 7 25 7 7 7 13 7 13 0 19 7 7 7 32 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % F
% Gly: 25 32 13 32 0 19 13 0 7 0 7 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 7 0 7 7 7 0 0 0 0 13 0 0 7 % I
% Lys: 7 7 0 13 13 0 7 13 13 0 7 19 44 7 0 % K
% Leu: 7 7 13 0 0 0 13 7 0 13 7 7 0 19 13 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 25 % M
% Asn: 0 0 0 19 13 0 13 7 0 0 19 0 7 0 0 % N
% Pro: 13 0 38 0 32 0 7 0 38 7 0 0 0 0 7 % P
% Gln: 0 7 0 0 7 0 0 0 0 0 0 7 19 7 13 % Q
% Arg: 7 7 13 7 7 7 7 0 0 0 0 19 7 0 13 % R
% Ser: 13 7 0 7 13 13 13 7 13 19 19 19 7 0 7 % S
% Thr: 0 0 0 7 0 7 13 25 7 0 13 7 0 7 7 % T
% Val: 13 7 0 0 0 19 7 7 13 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 7 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _