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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF40 All Species: 19.7
Human Site: Y214 Identified Species: 28.89
UniProt: O75150 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75150 NP_055586.1 1001 113678 Y214 E E L C Q R V Y S R G D S E P
Chimpanzee Pan troglodytes Q2TLZ5 664 76145
Rhesus Macaque Macaca mulatta XP_001102375 1094 123413 Y307 E E L C Q R V Y S R G D S E P
Dog Lupus familis XP_848895 1001 113606 Y214 E E L C Q R V Y S R G D S E P
Cat Felis silvestris
Mouse Mus musculus Q3U319 1001 113949 Y214 E E L C Q R V Y S R G D S E A
Rat Rattus norvegicus Q8CJB9 1002 113822 Y215 E E L C Q R V Y S R G D S E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521737 913 103647 A187 N R R L Q D L A T Q L Q E K H
Chicken Gallus gallus Q5ZLS3 984 114789 L206 V D V L S H K L N S G D I S L
Frog Xenopus laevis Q6DFL0 524 61335
Zebra Danio Brachydanio rerio Q6NZW0 581 66777
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP9 1044 119041 T211 S G D A E T T T S S A G V H A
Honey Bee Apis mellifera XP_625025 866 101052 L188 K D T F A L E L C N Q V E D L
Nematode Worm Caenorhab. elegans P34537 837 97425 I174 I D K L K T L I D S P T F N P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXD6 878 99700 R190 E L Y P T V L R T N L G K D L
Baker's Yeast Sacchar. cerevisiae Q07457 700 80674 I38 K E A L F R C I N R R R V D F
Red Bread Mold Neurospora crassa Q7S304 707 80536 Y45 E E A W I E E Y Q K G A I Y R
Conservation
Percent
Protein Identity: 100 20.9 90 96.4 N.A. 92.5 92.5 N.A. 70.5 58.9 20.6 20.3 N.A. 43 47.5 25 N.A.
Protein Similarity: 100 36.9 90.4 97.5 N.A. 95.1 95.2 N.A. 76.5 74 34 35.1 N.A. 60.5 62.2 46.3 N.A.
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. 6.6 13.3 0 0 N.A. 6.6 0 6.6 N.A.
P-Site Similarity: 100 0 100 100 N.A. 93.3 93.3 N.A. 33.3 33.3 0 0 N.A. 13.3 20 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.6 21.2 23.2
Protein Similarity: N.A. N.A. N.A. 44.2 39.6 40.4
P-Site Identity: N.A. N.A. N.A. 6.6 20 26.6
P-Site Similarity: N.A. N.A. N.A. 26.6 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 7 7 0 0 7 0 0 7 7 0 0 19 % A
% Cys: 0 0 0 32 0 0 7 0 7 0 0 0 0 0 0 % C
% Asp: 0 19 7 0 0 7 0 0 7 0 0 38 0 19 0 % D
% Glu: 44 44 0 0 7 7 13 0 0 0 0 0 13 32 0 % E
% Phe: 0 0 0 7 7 0 0 0 0 0 0 0 7 0 7 % F
% Gly: 0 7 0 0 0 0 0 0 0 0 44 13 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 7 % H
% Ile: 7 0 0 0 7 0 0 13 0 0 0 0 13 0 0 % I
% Lys: 13 0 7 0 7 0 7 0 0 7 0 0 7 7 0 % K
% Leu: 0 7 32 25 0 7 19 13 0 0 13 0 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 13 13 0 0 0 7 0 % N
% Pro: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 25 % P
% Gln: 0 0 0 0 38 0 0 0 7 7 7 7 0 0 0 % Q
% Arg: 0 7 7 0 0 38 0 7 0 38 7 7 0 0 7 % R
% Ser: 7 0 0 0 7 0 0 0 38 19 0 0 32 7 0 % S
% Thr: 0 0 7 0 7 13 7 7 13 0 0 7 0 0 0 % T
% Val: 7 0 7 0 0 7 32 0 0 0 0 7 13 0 0 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 38 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _