Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF40 All Species: 32.73
Human Site: Y976 Identified Species: 48
UniProt: O75150 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75150 NP_055586.1 1001 113678 Y976 F E C V R G R Y E A R Q R K C
Chimpanzee Pan troglodytes Q2TLZ5 664 76145 S648 S S K F V E T S P S G L D P N
Rhesus Macaque Macaca mulatta XP_001102375 1094 123413 Y1069 F E C V R G R Y E A R Q R K C
Dog Lupus familis XP_848895 1001 113606 Y976 F E C V R G R Y E A R Q R K C
Cat Felis silvestris
Mouse Mus musculus Q3U319 1001 113949 Y976 F E C V R G R Y E A R Q R K C
Rat Rattus norvegicus Q8CJB9 1002 113822 Y977 F E C V R G R Y E A R Q R K C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521737 913 103647 Q894 H I P A L L F Q L P S T F N G
Chicken Gallus gallus Q5ZLS3 984 114789 Y959 F E C V K T R Y D T R Q R K C
Frog Xenopus laevis Q6DFL0 524 61335 V508 R F S N D D A V D L G S D P D
Zebra Danio Brachydanio rerio Q6NZW0 581 66777 P565 P E D A D G P P S D P D E D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP9 1044 119041 Y1019 Y D C L R T R Y E T R Q R K C
Honey Bee Apis mellifera XP_625025 866 101052 Y840 W D C L R T R Y E T R Q R K C
Nematode Worm Caenorhab. elegans P34537 837 97425 P821 D T R Q R K C P K C N S N F G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXD6 878 99700 T854 N P C V Q K L T G T R Q K K C
Baker's Yeast Sacchar. cerevisiae Q07457 700 80674 P684 A A R M R K C P T C N K A F S
Red Bread Mold Neurospora crassa Q7S304 707 80536 P691 A N R M R K C P S C N K A F D
Conservation
Percent
Protein Identity: 100 20.9 90 96.4 N.A. 92.5 92.5 N.A. 70.5 58.9 20.6 20.3 N.A. 43 47.5 25 N.A.
Protein Similarity: 100 36.9 90.4 97.5 N.A. 95.1 95.2 N.A. 76.5 74 34 35.1 N.A. 60.5 62.2 46.3 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 0 73.3 0 13.3 N.A. 66.6 66.6 6.6 N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 0 86.6 6.6 13.3 N.A. 86.6 86.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.6 21.2 23.2
Protein Similarity: N.A. N.A. N.A. 44.2 39.6 40.4
P-Site Identity: N.A. N.A. N.A. 40 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 53.3 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 7 0 13 0 0 7 0 0 32 0 0 13 0 0 % A
% Cys: 0 0 57 0 0 0 19 0 0 19 0 0 0 0 57 % C
% Asp: 7 13 7 0 13 7 0 0 13 7 0 7 13 7 13 % D
% Glu: 0 44 0 0 0 7 0 0 44 0 0 0 7 0 7 % E
% Phe: 38 7 0 7 0 0 7 0 0 0 0 0 7 19 0 % F
% Gly: 0 0 0 0 0 38 0 0 7 0 13 0 0 0 13 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 0 7 25 0 0 7 0 0 13 7 57 0 % K
% Leu: 0 0 0 13 7 7 7 0 7 7 0 7 0 0 0 % L
% Met: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 0 7 0 0 0 0 0 0 19 0 7 7 7 % N
% Pro: 7 7 7 0 0 0 7 25 7 7 7 0 0 13 0 % P
% Gln: 0 0 0 7 7 0 0 7 0 0 0 57 0 0 0 % Q
% Arg: 7 0 19 0 63 0 50 0 0 0 57 0 50 0 0 % R
% Ser: 7 7 7 0 0 0 0 7 13 7 7 13 0 0 7 % S
% Thr: 0 7 0 0 0 19 7 7 7 25 0 7 0 0 0 % T
% Val: 0 0 0 44 7 0 0 7 0 0 0 0 0 0 0 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _