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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0664
All Species:
29.39
Human Site:
S281
Identified Species:
53.89
UniProt:
O75153
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75153
NP_056044.3
1309
146670
S281
S
P
R
F
L
S
H
S
L
V
E
L
L
N
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548323
1501
166268
S473
S
P
R
F
L
S
H
S
L
V
E
L
L
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q5SW19
1315
148050
S281
S
P
R
F
L
S
H
S
L
V
E
L
L
N
Q
Rat
Rattus norvegicus
XP_001080615
1352
151608
S322
S
P
R
F
L
S
H
S
L
V
E
L
L
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509391
982
108607
R76
I
H
Q
V
L
M
D
R
E
D
T
C
H
R
T
Chicken
Gallus gallus
XP_415920
1293
145294
S317
N
P
S
F
L
S
H
S
L
V
E
L
L
N
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A0JMD0
1400
155792
S326
N
P
S
F
L
S
H
S
L
V
E
L
L
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAB5
1448
160833
S370
N
P
S
H
L
S
H
S
L
I
D
L
L
S
H
Honey Bee
Apis mellifera
XP_624898
1290
145677
S302
T
P
S
H
L
C
H
S
L
I
E
L
L
N
Q
Nematode Worm
Caenorhab. elegans
P34466
1247
139903
Q275
N
S
N
K
T
V
Y
Q
S
V
I
E
L
L
Q
Sea Urchin
Strong. purpuratus
XP_001198284
1101
124381
V196
S
L
S
F
L
S
T
V
L
S
E
G
V
L
F
Poplar Tree
Populus trichocarpa
XP_002314020
1343
146561
G274
L
P
P
C
S
W
L
G
L
Y
P
V
P
D
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RY84
1211
135142
I255
P
S
I
N
S
S
L
I
A
H
E
A
D
N
T
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.3
N.A.
94.9
89.9
N.A.
60.8
83.1
N.A.
75
N.A.
52
59.8
39.9
51.9
Protein Similarity:
100
N.A.
N.A.
85.5
N.A.
96.9
92.7
N.A.
67.2
89.3
N.A.
83.6
N.A.
69
75.7
59.5
63.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
86.6
N.A.
80
N.A.
53.3
66.6
20
40
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
93.3
N.A.
93.3
N.A.
80
80
33.3
46.6
Percent
Protein Identity:
27.3
N.A.
N.A.
N.A.
N.A.
29
Protein Similarity:
46.6
N.A.
N.A.
N.A.
N.A.
48.9
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
8
8
0
8
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
70
8
0
0
0
% E
% Phe:
0
0
0
54
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% G
% His:
0
8
0
16
0
0
62
0
0
8
0
0
8
0
16
% H
% Ile:
8
0
8
0
0
0
0
8
0
16
8
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
0
0
77
0
16
0
77
0
0
62
70
16
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
31
0
8
8
0
0
0
0
0
0
0
0
0
54
0
% N
% Pro:
8
70
8
0
0
0
0
0
0
0
8
0
8
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
62
% Q
% Arg:
0
0
31
0
0
0
0
8
0
0
0
0
0
8
0
% R
% Ser:
39
16
39
0
16
70
0
62
8
8
0
0
0
16
0
% S
% Thr:
8
0
0
0
8
0
8
0
0
0
8
0
0
0
16
% T
% Val:
0
0
0
8
0
8
0
8
0
54
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _