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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0664 All Species: 2.42
Human Site: S652 Identified Species: 4.44
UniProt: O75153 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75153 NP_056044.3 1309 146670 S652 G G P S S L E S K S E D P P G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548323 1501 166268 S844 G D S P S S A S K P E D S P G
Cat Felis silvestris
Mouse Mus musculus Q5SW19 1315 148050 K654 L P S S A E T K S E D S I G P
Rat Rattus norvegicus XP_001080615 1352 151608 K695 P P S S T E T K S E D S L G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509391 982 108607 L386 V V S H P R Y L E L L E K T G
Chicken Gallus gallus XP_415920 1293 145294 G687 N G T S P E N G T A E S E K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A0JMD0 1400 155792 Q762 E P L A A E R Q N G G C D G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAB5 1448 160833 K755 G A E K P D D K E K K N E E E
Honey Bee Apis mellifera XP_624898 1290 145677 R664 R V Q K E S K R E E L N T V A
Nematode Worm Caenorhab. elegans P34466 1247 139903 I632 A K K I R D L I T E S K E K N
Sea Urchin Strong. purpuratus XP_001198284 1101 124381 E505 F D L D G L Y E L G T V V V D
Poplar Tree Populus trichocarpa XP_002314020 1343 146561 A607 E G G A H V A A D S T E V T T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RY84 1211 135142 E567 A T E E A K T E E I K T E E A
Conservation
Percent
Protein Identity: 100 N.A. N.A. 83.3 N.A. 94.9 89.9 N.A. 60.8 83.1 N.A. 75 N.A. 52 59.8 39.9 51.9
Protein Similarity: 100 N.A. N.A. 85.5 N.A. 96.9 92.7 N.A. 67.2 89.3 N.A. 83.6 N.A. 69 75.7 59.5 63.7
P-Site Identity: 100 N.A. N.A. 53.3 N.A. 6.6 6.6 N.A. 6.6 20 N.A. 0 N.A. 6.6 0 0 6.6
P-Site Similarity: 100 N.A. N.A. 53.3 N.A. 20 20 N.A. 20 26.6 N.A. 13.3 N.A. 33.3 20 0 6.6
Percent
Protein Identity: 27.3 N.A. N.A. N.A. N.A. 29
Protein Similarity: 46.6 N.A. N.A. N.A. N.A. 48.9
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 40 N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 16 24 0 16 8 0 8 0 0 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 16 0 8 0 16 8 0 8 0 16 16 8 0 8 % D
% Glu: 16 0 16 8 8 31 8 16 31 31 24 16 31 16 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 24 24 8 0 8 0 0 8 0 16 8 0 0 24 24 % G
% His: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 8 0 8 0 0 8 0 0 % I
% Lys: 0 8 8 16 0 8 8 24 16 8 16 8 8 16 0 % K
% Leu: 8 0 16 0 0 16 8 8 8 8 16 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 8 0 8 0 0 16 0 0 8 % N
% Pro: 8 24 8 8 24 0 0 0 0 8 0 0 8 16 16 % P
% Gln: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 8 8 8 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 31 31 16 16 0 16 16 16 8 24 8 0 16 % S
% Thr: 0 8 8 0 8 0 24 0 16 0 16 8 8 16 8 % T
% Val: 8 16 0 0 0 8 0 0 0 0 0 8 16 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _