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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS5
All Species:
36.06
Human Site:
S418
Identified Species:
79.33
UniProt:
O75159
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75159
NP_054730.1
536
61246
S418
E
D
Y
L
F
S
V
S
F
R
R
Y
N
R
S
Chimpanzee
Pan troglodytes
XP_509960
440
50619
H332
R
R
Y
S
R
S
L
H
A
R
I
E
Q
W
N
Rhesus Macaque
Macaca mulatta
XP_001113221
536
61242
S418
E
D
Y
L
F
S
V
S
F
R
R
Y
N
R
S
Dog
Lupus familis
XP_531810
536
61259
S418
E
D
Y
L
F
S
V
S
F
R
R
Y
N
R
S
Cat
Felis silvestris
Mouse
Mus musculus
O54928
536
61097
S418
E
D
Y
L
F
S
V
S
F
R
R
Y
N
R
S
Rat
Rattus norvegicus
NP_001102744
536
61147
S418
E
D
Y
L
F
S
V
S
F
R
R
Y
N
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001120786
536
61266
S418
E
D
Y
L
F
S
V
S
F
R
R
Y
N
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341479
620
69431
S501
E
D
Y
L
F
S
V
S
F
R
R
Y
N
R
S
Tiger Blowfish
Takifugu rubipres
NP_001116333
550
60455
S431
E
D
Y
L
F
S
V
S
F
R
R
Y
N
R
S
Fruit Fly
Dros. melanogaster
NP_724096
633
68884
T511
E
E
F
L
F
S
V
T
F
R
K
Y
G
R
S
Honey Bee
Apis mellifera
XP_624419
475
53901
F367
Q
W
N
H
K
F
S
F
D
S
H
D
P
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44
99.6
97.5
N.A.
94.5
95.1
N.A.
N.A.
91
N.A.
60.9
65.4
29.7
35.2
N.A.
N.A.
Protein Similarity:
100
59.5
100
99.2
N.A.
97.1
97.9
N.A.
N.A.
95.1
N.A.
70
76.1
44.5
50.1
N.A.
N.A.
P-Site Identity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
100
66.6
0
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
100
93.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
73
0
0
0
0
0
0
10
0
0
10
0
0
0
% D
% Glu:
82
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
10
0
82
10
0
10
82
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
82
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
73
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
10
0
0
10
0
0
0
0
91
73
0
0
82
0
% R
% Ser:
0
0
0
10
0
91
10
73
0
10
0
0
0
0
82
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
82
0
0
0
0
0
0
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
82
0
0
0
0
0
0
0
0
82
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _