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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS4
All Species:
13.33
Human Site:
T437
Identified Species:
36.67
UniProt:
O75173
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75173
NP_005090.3
837
90225
T437
A
P
L
H
L
P
V
T
F
P
G
K
D
Y
D
Chimpanzee
Pan troglodytes
XP_513940
837
90177
T437
A
P
L
H
L
P
V
T
F
P
G
K
D
Y
D
Rhesus Macaque
Macaca mulatta
XP_001103864
967
105507
D476
N
P
I
Q
L
P
G
D
L
P
G
T
S
Y
D
Dog
Lupus familis
XP_545768
839
90029
T439
A
P
L
H
L
P
V
T
F
P
G
K
D
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNJ2
833
90051
T433
A
P
L
H
L
P
A
T
F
P
G
K
D
Y
D
Rat
Rattus norvegicus
Q9ESP7
630
68366
Q276
L
N
G
H
A
M
C
Q
T
K
H
S
P
W
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416687
924
100633
D419
R
P
I
Q
L
P
S
D
L
P
G
T
L
Y
D
Frog
Xenopus laevis
NP_001088627
928
102191
D426
R
P
I
Q
L
P
S
D
L
P
G
T
L
Y
D
Zebra Danio
Brachydanio rerio
NP_001119901
958
105214
V430
K
P
L
A
L
P
D
V
L
P
G
A
S
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
45
92.3
N.A.
90.3
69.5
N.A.
N.A.
42.9
41.8
39.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
58.6
95.1
N.A.
93
71.9
N.A.
N.A.
56.8
55.1
52
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
46.6
100
N.A.
93.3
6.6
N.A.
N.A.
46.6
46.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
53.3
100
N.A.
93.3
13.3
N.A.
N.A.
53.3
53.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
0
12
12
0
12
0
0
0
0
12
0
0
12
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
34
0
0
0
0
45
0
78
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
45
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
12
0
0
0
89
0
0
0
12
% G
% His:
0
0
0
56
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
0
12
0
45
0
0
0
% K
% Leu:
12
0
56
0
89
0
0
0
45
0
0
0
23
0
0
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
89
0
0
0
89
0
0
0
89
0
0
12
0
0
% P
% Gln:
0
0
0
34
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
23
0
0
0
0
12
23
0
0
% S
% Thr:
0
0
0
0
0
0
0
45
12
0
0
34
0
0
0
% T
% Val:
0
0
0
0
0
0
34
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
89
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _