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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNOT3 All Species: 15.15
Human Site: S245 Identified Species: 33.33
UniProt: O75175 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75175 NP_055331.1 753 81872 S245 L V A T S P P S H S H M E D E
Chimpanzee Pan troglodytes XP_512885 688 76993 L183 H R Y H V R M L E T I L R M L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541428 752 81536 S245 L V A T S P P S H S H M E D E
Cat Felis silvestris
Mouse Mus musculus Q8K0V4 751 81927 S245 L V A T S P P S H S H M E D E
Rat Rattus norvegicus NP_001100941 751 81862 S245 L V A T S P P S H S H M E D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001086992 728 81088 F220 D S S Q D P D F E E N E F L Y
Zebra Danio Brachydanio rerio NP_956134 908 96903 G245 V V P T S P A G H P D D E I F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610176 844 92349 S249 S G T A T T D S N N S N E T S
Honey Bee Apis mellifera XP_395261 684 76726 I179 L D K H R Y H I R K L E T L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203995 878 98224 E245 A T S P D D E E N H M D D D T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P06102 836 94385 F246 A H E V A Q Y F A S Q N A E D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.9 N.A. 96.6 N.A. 95.2 95.4 N.A. N.A. N.A. 77.1 54.2 N.A. 41.5 51.9 N.A. 45.3
Protein Similarity: 100 88.1 N.A. 97.6 N.A. 96.4 96.6 N.A. N.A. N.A. 84 63.9 N.A. 57.7 65.7 N.A. 58.5
P-Site Identity: 100 0 N.A. 100 N.A. 100 100 N.A. N.A. N.A. 6.6 40 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 100 N.A. N.A. N.A. 20 46.6 N.A. 33.3 6.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 37 10 10 0 10 0 10 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 0 19 10 19 0 0 0 10 19 10 46 10 % D
% Glu: 0 0 10 0 0 0 10 10 19 10 0 19 55 10 37 % E
% Phe: 0 0 0 0 0 0 0 19 0 0 0 0 10 0 10 % F
% Gly: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 10 10 0 19 0 0 10 0 46 10 37 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 10 0 0 10 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 46 0 0 0 0 0 0 10 0 0 10 10 0 19 19 % L
% Met: 0 0 0 0 0 0 10 0 0 0 10 37 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 19 10 10 19 0 0 0 % N
% Pro: 0 0 10 10 0 55 37 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 10 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 10 0 0 10 10 0 0 10 0 0 0 10 0 0 % R
% Ser: 10 10 19 0 46 0 0 46 0 46 10 0 0 0 10 % S
% Thr: 0 10 10 46 10 10 0 0 0 10 0 0 10 10 10 % T
% Val: 10 46 0 10 10 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 10 10 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _