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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNOT3 All Species: 9.09
Human Site: S396 Identified Species: 20
UniProt: O75175 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75175 NP_055331.1 753 81872 S396 R P P S V Q P S G G G G G G S
Chimpanzee Pan troglodytes XP_512885 688 76993 L334 P P P A A S A L S T T P G N N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541428 752 81536 G396 R P P S V Q P G G G G G S G G
Cat Felis silvestris
Mouse Mus musculus Q8K0V4 751 81927 S396 R P P S A Q P S G G S G G G S
Rat Rattus norvegicus NP_001100941 751 81862 S396 R P P S A Q P S G G S G G G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001086992 728 81088 A371 S N S K N N P A S G H T S G T
Zebra Danio Brachydanio rerio NP_956134 908 96903 T396 S N S I L L P T S A S T S P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610176 844 92349 Q400 S T P S K N Q Q Q L P T A A S
Honey Bee Apis mellifera XP_395261 684 76726 P330 N L L S S S T P S K T I P M T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203995 878 98224 S396 P R K G S A K S T S S S S S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P06102 836 94385 P397 P A T L P A K P A G E L K W A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.9 N.A. 96.6 N.A. 95.2 95.4 N.A. N.A. N.A. 77.1 54.2 N.A. 41.5 51.9 N.A. 45.3
Protein Similarity: 100 88.1 N.A. 97.6 N.A. 96.4 96.6 N.A. N.A. N.A. 84 63.9 N.A. 57.7 65.7 N.A. 58.5
P-Site Identity: 100 20 N.A. 80 N.A. 86.6 86.6 N.A. N.A. N.A. 20 6.6 N.A. 20 6.6 N.A. 6.6
P-Site Similarity: 100 33.3 N.A. 80 N.A. 86.6 86.6 N.A. N.A. N.A. 33.3 20 N.A. 20 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 28 19 10 10 10 10 0 0 10 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 10 37 55 19 37 37 46 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 10 10 10 0 19 0 0 10 0 0 10 0 0 % K
% Leu: 0 10 10 10 10 10 0 10 0 10 0 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 10 19 0 0 10 19 0 0 0 0 0 0 0 10 10 % N
% Pro: 28 46 55 0 10 0 55 19 0 0 10 10 10 10 10 % P
% Gln: 0 0 0 0 0 37 10 10 10 0 0 0 0 0 0 % Q
% Arg: 37 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 28 0 19 55 19 19 0 37 37 10 37 10 37 10 37 % S
% Thr: 0 10 10 0 0 0 10 10 10 10 19 28 0 0 19 % T
% Val: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _