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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SS18L1 All Species: 17.27
Human Site: S225 Identified Species: 38
UniProt: O75177 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75177 NP_945173.1 396 42990 S225 G Q G S Q G S S M M G Q R P M
Chimpanzee Pan troglodytes XP_514762 407 44081 S225 G Q G S Q G S S M M G Q R P M
Rhesus Macaque Macaca mulatta XP_001089944 373 40539 M203 Q G S Q G S S M M G Q R P M A
Dog Lupus familis XP_543083 678 72149 M397 Q S G Q G S S M M G Q R P M A
Cat Felis silvestris
Mouse Mus musculus Q62280 418 45873 Y225 P P G G A Q H Y Q G Q Q A P M
Rat Rattus norvegicus NP_620273 401 43980 S230 G P G W Q G G S M M G Q R P M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505924 399 44048 S228 S Q S N Q G N S M M G Q R P M
Chicken Gallus gallus XP_417402 402 44106 S231 S Q S N Q G N S M M G Q R P M
Frog Xenopus laevis NP_001087101 403 44198 Q225 P S I A M M N Q S S Q G S S M
Zebra Danio Brachydanio rerio NP_956038 368 40152 M198 Q P N Q G P M M H Q Q A P S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624990 608 63687 V222 N Y G P P T T V N S Y G P Q P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82 93.6 53.3 N.A. 60.7 84.7 N.A. 83.2 86.3 79.4 53.2 N.A. N.A. 30.5 N.A. N.A.
Protein Similarity: 100 85.5 93.6 55.5 N.A. 70.8 89.2 N.A. 88.9 91.7 87.8 64.1 N.A. N.A. 37.6 N.A. N.A.
P-Site Identity: 100 100 13.3 20 N.A. 26.6 80 N.A. 73.3 73.3 6.6 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 20 26.6 N.A. 26.6 80 N.A. 86.6 86.6 20 0 N.A. N.A. 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 0 0 0 0 10 10 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 28 10 55 10 28 46 10 0 0 28 46 19 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 10 10 10 28 64 46 0 0 0 19 64 % M
% Asn: 10 0 10 19 0 0 28 0 10 0 0 0 0 0 0 % N
% Pro: 19 28 0 10 10 10 0 0 0 0 0 0 37 55 10 % P
% Gln: 28 37 0 28 46 10 0 10 10 10 46 55 0 10 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 19 46 0 0 % R
% Ser: 19 19 28 19 0 19 37 46 10 19 0 0 10 19 0 % S
% Thr: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 10 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _