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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
16.06
Human Site:
S1040
Identified Species:
29.44
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
S1040
A
L
R
G
E
A
R
S
S
W
K
R
L
V
G
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
S1037
A
L
R
G
E
A
R
S
S
W
K
R
L
V
G
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
N1088
E
K
E
G
K
E
G
N
S
K
K
T
M
E
N
Dog
Lupus familis
XP_852728
1090
125608
V982
G
V
E
S
A
C
N
V
D
C
R
F
K
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
E985
W
K
R
L
M
G
V
E
S
A
C
D
V
D
C
Rat
Rattus norvegicus
NP_001102231
1129
127784
E1016
L
Q
H
I
V
S
D
E
V
C
V
Q
V
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
S994
A
L
R
N
E
V
K
S
S
W
K
R
L
I
G
Chicken
Gallus gallus
XP_418257
1273
146269
S1151
A
L
R
S
E
V
K
S
S
W
K
R
L
I
G
Frog
Xenopus laevis
NP_001090601
1125
130319
S1003
V
M
K
D
E
V
K
S
S
W
K
K
L
M
G
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
R1073
V
E
A
M
R
C
R
R
E
W
H
R
K
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
G1164
E
G
R
V
V
V
G
G
V
M
N
P
L
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
N1181
V
V
A
D
E
M
D
N
K
L
L
Q
L
Y
F
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
P1395
T
L
K
I
K
I
Q
P
I
T
Y
Q
L
H
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
20
0
N.A.
13.3
0
N.A.
73.3
73.3
46.6
26.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
40
20
N.A.
20
20
N.A.
86.6
86.6
80
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
16
0
8
16
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
16
0
0
0
16
8
0
0
0
8
% C
% Asp:
0
0
0
16
0
0
16
0
8
0
0
8
0
8
8
% D
% Glu:
16
8
16
0
47
8
0
16
8
0
0
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% F
% Gly:
8
8
0
24
0
8
16
8
0
0
0
0
0
0
54
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
0
0
16
0
8
0
0
8
0
0
0
0
16
8
% I
% Lys:
0
16
16
0
16
0
24
0
8
8
47
8
16
0
0
% K
% Leu:
8
39
0
8
0
0
0
0
0
8
8
0
62
8
0
% L
% Met:
0
8
0
8
8
8
0
0
0
8
0
0
8
16
0
% M
% Asn:
0
0
0
8
0
0
8
16
0
0
8
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
24
0
0
0
% Q
% Arg:
0
0
47
0
8
0
24
8
0
0
8
39
0
0
0
% R
% Ser:
0
0
0
16
0
8
0
39
54
0
0
0
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% T
% Val:
24
16
0
8
16
31
8
8
16
0
8
0
16
16
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
47
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _